Voveran 50 GE Tablet 15′

Voveran 50 GE Tablet is a prescription medication manufactured by Novartis India Ltd. It contains Diclofenac (50 mg), a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with various conditions, such as arthritis, musculoskeletal disorders, and other painful conditions.

Composition:

• Diclofenac (50 mg) – The active ingredient in Voveran 50 GE Tablet is Diclofenac, a potent NSAID that helps reduce pain, inflammation, and fever by inhibiting the production of prostaglandins (chemicals in the body that promote inflammation).
• GE: The “GE” in the product name refers to the Gastro-Resistant or Gastro-Enhanced formulation, designed to protect the stomach from potential irritation caused by diclofenac. This formulation helps the tablet pass through the stomach and dissolve in the intestines, where it is absorbed, reducing the risk of gastrointestinal side effects like ulcers or bleeding.

Mechanism of Action:

• Diclofenac works by inhibiting the enzyme cyclooxygenase (COX-1 and COX-2), which is responsible for the production of prostaglandins. Prostaglandins are chemicals involved in inflammation, pain, and fever. By blocking the action of COX, diclofenac helps reduce inflammation, pain, and fever.
• The gastro-resistant formulation of Voveran 50 GE Tablet ensures that diclofenac is released in the intestines rather than in the stomach, thus reducing the risk of stomach-related side effects like acidity or ulcers.

Indications:

Voveran 50 GE Tablet is commonly used for the treatment of:

1. Osteoarthritis: A degenerative joint disease characterized by pain, stiffness, and inflammation in the joints.
2. Rheumatoid Arthritis: An autoimmune condition that causes chronic inflammation in the joints, leading to pain and damage.
3. Ankylosing Spondylitis: An inflammatory disease primarily affecting the spine and large joints, causing pain and stiffness.
4. Musculoskeletal Pain: For conditions like sprains, strains, and injuries affecting muscles or soft tissues.
5. Postoperative Pain: To manage pain following surgery.
6. Dysmenorrhea (Menstrual Pain): For relieving pain associated with menstruation.

Dosage:

The usual dosage of Voveran 50 GE Tablet is 50 mg taken one to two times a day depending on the severity of the condition and the advice of your healthcare provider.

• Osteoarthritis and Rheumatoid Arthritis: 50 mg to 100 mg daily in divided doses.
• Ankylosing Spondylitis and Musculoskeletal Pain: 50 mg once or twice a day.
• Postoperative Pain: The dose will be determined by your doctor based on the severity of pain.
• Dysmenorrhea (Menstrual Pain): Usually 50 mg every 4–6 hours as needed.

Important: Always follow the dosage instructions given by your healthcare provider, and do not exceed the recommended dose.

Side Effects:

Common side effects of Voveran 50 GE Tablet may include:

• Gastrointestinal Issues:
  • Nausea, indigestion, or upset stomach
  • Diarrhea or constipation
  • Stomach ulcers or bleeding (with long-term use)
• Cardiovascular Effects:
  • Increased blood pressure
  • Fluid retention or swelling (edema)
  • Long-term use may increase the risk of heart attack, stroke, or other cardiovascular issues.
• Kidney or Liver Effects:
  • Potential for kidney damage or dysfunction with prolonged use.
  • Elevation of liver enzymes (usually monitored during long-term therapy).
• Skin Reactions:
  • Rash or itching in some people.
• Allergic Reactions (less common):
  • Difficulty breathing, swelling of the face or throat, severe skin reactions.

Precautions:

• Gastrointestinal Risk:
  • NSAIDs like diclofenac can increase the risk of stomach ulcers, bleeding, or gastrointestinal perforation. This risk is higher with long-term use or in patients with a history of stomach ulcers.
• Cardiovascular Risk:
  • Diclofenac may increase the risk of heart attack or stroke in patients with existing heart disease or in those using it long-term. It is important to use this drug at the lowest effective dose for the shortest duration necessary.
• Kidney and Liver Health:
  • Prolonged use of diclofenac can affect kidney and liver function. Kidney function should be monitored, particularly in elderly patients or those with pre-existing kidney problems.
• Pregnancy and Breastfeeding:
  • Pregnancy: Voveran 50 GE Tablet should be avoided, especially during the third trimester, as it may harm the developing fetus.
  • Breastfeeding: Diclofenac is excreted in breast milk, so it should only be used during breastfeeding if absolutely necessary and under the guidance of a healthcare provider.
• Drug Interactions:
  • Blood pressure medications (like ACE inhibitors and diuretics), anticoagulants (such as warfarin), and other NSAIDs may interact with diclofenac. Always inform your doctor about all the medications you are taking.

Storage:

• Voveran 50 GE Tablet should be stored at room temperature, below 30°C.
• Keep it in a dry place and away from moisture and heat.
• Keep out of reach of children.

Return Policy:

• Voveran 50 GE Tablet is a prescription medication, and like most prescription drugs, it is non-returnable once purchased.