Udiliv 150mg Tablet

Udiliv 150mg Tablet is a prescription medication marketed by Abbott and contains Ursodeoxycholic Acid (150 mg) as the active ingredient. It is used for various liver and gallbladder disorders and works by improving bile flow and reducing cholesterol saturation in bile.

Composition:

• Ursodeoxycholic Acid (150 mg) – The active ingredient, which is a naturally occurring bile acid. It is also known as Ursodiol.

Mechanism of Action:

• Ursodeoxycholic Acid (UDCA) works by:
  • Reducing cholesterol saturation in bile, which helps to dissolve cholesterol gallstones and prevent the formation of new stones.
  • Improving bile flow in conditions where bile is not properly secreted or flows inadequately (e.g., cholestasis).
  • Protecting liver cells from damage caused by toxic bile acids, especially in conditions like primary biliary cirrhosis (PBC).

Indications:

Udiliv 150mg Tablet is used to treat several liver and gallbladder disorders:

1. Cholesterol Gallstones:
   • Ursodeoxycholic acid helps dissolve small, non-calcified cholesterol gallstones in patients who are not candidates for surgery.
2. Primary Biliary Cirrhosis (PBC):
   • It is used to treat PBC, a condition where the bile ducts in the liver are damaged, which can lead to cirrhosis. UDCA helps improve liver function and slow the disease’s progression.
3. Non-alcoholic Fatty Liver Disease (NAFLD):
   • UDCA may be used to improve liver function in some patients with NAFLD, though its use is typically considered when other treatments are insufficient.
4. Cholestasis:
   • A condition where bile cannot flow properly from the liver to the duodenum. UDCA helps restore bile flow and reduce symptoms.
5. Liver Protection:
   • UDCA is used to reduce the toxic effects of bile acids in patients with liver dysfunction.

Dosage:

The typical dose of Udiliv 150mg Tablet varies based on the condition being treated:

• For gallstones: Usually, 150 mg to 300 mg per day (divided doses). Treatment typically lasts several months.
• For primary biliary cirrhosis (PBC): The recommended dose is typically 13-15 mg/kg body weight per day, but it should be individualized.
• For other liver disorders: Dosage should be adjusted based on the severity of the condition and as directed by a healthcare provider.

Important: Always follow the exact dosage prescribed by your doctor, as the treatment duration and dose may vary depending on the condition.

Side Effects:

Udiliv 150mg Tablet is generally well-tolerated, but possible side effects include:

• Common side effects:
  • Diarrhea
  • Abdominal pain
  • Nausea or vomiting
  • Headache
• Less common but serious side effects:
  • Allergic reactions (rash, itching, swelling)
  • Liver function abnormalities: Monitoring may be required, especially in those with existing liver issues.
  • Fatigue or weakness
  • Yellowing of skin or eyes (jaundice): This could indicate a worsening of liver function and requires immediate medical attention.

If you experience severe side effects, contact your healthcare provider immediately.

Precautions:

• Pregnancy and Breastfeeding:
  • Ursodeoxycholic acid is generally considered safe during pregnancy (Category B), but it should only be used when the benefits outweigh the risks.
  • It is excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before using it.
• Liver Disease:
  • While Ursodeoxycholic acid is used to treat liver conditions, caution should be exercised if there is severe liver impairment. Liver function should be monitored during treatment.
• Gallstones:
  • Ursodeoxycholic acid is effective for cholesterol gallstones, but it is not effective for calcified or large gallstones. It should not be used in cases of biliary tract obstruction.
• Drug Interactions:
  • Cholestyramine and Colestipol (bile acid sequestrants) may reduce the absorption of UDCA, so they should be taken at least 1 hour before or 4-6 hours after UDCA.
  • Ciclosporin (used in organ transplant patients) may have increased blood levels when taken with UDCA, so monitoring may be required.

Storage:

• Store Udiliv 150mg Tablet at room temperature, below 30°C.
• Keep the medication in a dry, cool place and protect it from excessive moisture and heat.
• Keep it out of reach of children.

Return Policy:

• Udiliv 150mg Tablet is not returnable, so ensure that the correct medication and quantity are ordered according to the prescription.