Description

Amdepin-AT – Strip of 14 Tablets

Amdepin 2.5 is a medication used for the treatment of high blood pressure (hypertension) and angina (chest pain). It contains the active ingredient Amlodipine, which is a calcium channel blocker. Amlodipine works by relaxing the blood vessels, improving blood flow, and thereby lowering blood pressure and reducing the workload on the heart.

Product Details:

• Brand Name: Amdepin 2.5
• Form: Tablet
• Strength: 2.5 mg
• Pack Size: Strip of 15 tablets

Composition:

• Active Ingredient:
  • Amlodipine (as Amlodipine Besylate) 2.5 mg per tablet.
• Excipients: These are inactive ingredients used to stabilize the tablet, such as binders and fillers. The exact composition can vary but typically includes substances that help the tablet maintain its shape and consistency.

Indications:

Amdepin 2.5 mg is used for:

• Hypertension (High Blood Pressure): Amlodipine helps to lower high blood pressure, thereby reducing the risk of heart attack, stroke, and kidney problems.
• Angina (Chest Pain): Amlodipine is used to treat and prevent angina, a type of chest pain caused by restricted blood flow to the heart.
• Coronary Artery Disease (CAD): It can also be used in the treatment of coronary artery disease by improving blood flow to the heart.

Mechanism of Action:

Amlodipine is a calcium channel blocker. It works by inhibiting the movement of calcium ions into smooth muscle and cardiac muscle cells, leading to:

• Relaxation of blood vessels (vasodilation), reducing the resistance the heart needs to pump against, which lowers blood pressure.
• Improved blood flow to the heart, which helps in preventing or relieving angina (chest pain).

Dosage and Administration:

• Adults: The usual starting dose for hypertension or angina is 5 mg once daily. Depending on the patient’s response, the dose can be adjusted to 2.5 mg or 10 mg daily. The dose of 2.5 mg is typically used for patients who are more sensitive to the drug, such as those with lower blood pressure or who are elderly.
• Children (6 to 17 years): The starting dose is 2.5 mg once daily, with a maximum dose of 5 mg daily.
• Administration: Take Amdepin 2.5 mg once a day, at the same time each day, with or without food.

Precautions:

• Pregnancy and Breastfeeding: Consult your doctor before using Amdepin if you are pregnant, planning to become pregnant, or breastfeeding. Amlodipine should be used during pregnancy only if absolutely necessary.
• Liver and Kidney Issues: Caution is required for patients with liver or kidney problems. Dose adjustments may be needed.
• Low Blood Pressure (Hypotension): Amdepin should be used cautiously in patients who already have low blood pressure, as it may cause a further drop in blood pressure.
• Heart Conditions: Patients with heart failure or certain heart conditions should consult their doctor before using Amdepin.

Side Effects:

Common side effects of Amdepin 2.5 mg may include:

• Swelling (edema), especially in the legs, feet, or ankles.
• Headache.
• Dizziness or lightheadedness, particularly when standing up quickly.
• Fatigue or feeling tired.
• Flushing (a feeling of warmth).
• Stomach discomfort or nausea.

Serious Side Effects:

• Severe allergic reactions: Symptoms like rash, itching, swelling of the face or throat, and difficulty breathing. Immediate medical attention is required if any of these symptoms occur.
• Chest pain, irregular heartbeats, or palpitations.
• Severe dizziness, fainting, or lightheadedness.
• Shortness of breath or worsening of heart failure symptoms.

If any serious side effects occur, seek medical help immediately.

Drug Interactions:

Amdepin 2.5 mg can interact with several medications:

• Other antihypertensive drugs: Combining Amdepin with other blood pressure-lowering medications may cause an additive effect, leading to excessively low blood pressure.
• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, some HIV medications): These drugs can increase Amlodipine’s blood levels, possibly leading to increased side effects.
• Grapefruit juice: This can increase Amlodipine levels and may result in low blood pressure.

Always inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins.

Storage:

• Store Amdepin 2.5 mg tablets in a cool, dry place at room temperature, away from direct sunlight and moisture.
• Keep the tablets in their original packaging and out of reach of children.

Key Notes:

• Amdepin 2.5 mg is effective for treating high blood pressure and angina.
• Take the medication as prescribed by your doctor and avoid skipping doses.
• Lifestyle modifications such as maintaining a healthy diet, exercising regularly, and reducing salt intake can enhance the effectiveness of the medication.
• Keep regular follow-up appointments to monitor blood pressure and any potential side effects.

Important: Always consult your healthcare provider before starting or making any changes to your medication regimen.