Description
Zita Met Plus 20 mg/500 mg – Strip of 15 Tablets is a combination medication primarily used to manage type 2 diabetes. It helps to control blood sugar levels in patients whose diabetes cannot be controlled by diet and exercise alone.
Composition:
Each uncoated bilayer tablet of Zita Met Plus 20 mg/500 mg contains:
- Teneligliptin Hydrobromide Hydrate (20 mg): This is the active ingredient in the DPP-4 inhibitor class of drugs. Teneligliptin helps increase insulin secretion from the pancreas and decreases the release of glucagon (a hormone that raises blood sugar levels). This helps to lower blood sugar levels after meals and improves overall glucose control.
- Metformin Hydrochloride I.P. (500 mg) (As Extended Release): Metformin is a biguanide medication that works by reducing glucose production in the liver and improving the body’s sensitivity to insulin. It is the first-line treatment for type 2 diabetes and helps in controlling blood sugar levels effectively.
Uses:
Zita Met Plus is prescribed to:
- Control blood sugar levels in adults with type 2 diabetes mellitus.
- It is typically used when diet and exercise alone cannot adequately control blood sugar.
- The combination of Teneligliptin and Metformin works synergistically to improve glucose control by both increasing insulin secretion and reducing the production of glucose by the liver.
Dosage:
The dosage of Zita Met Plus 20 mg/500 mg should be determined by a healthcare provider based on the patient’s individual condition. A typical dosage might be:
- Adults: One tablet (20 mg of Teneligliptin + 500 mg of Metformin) once daily, usually with a meal to minimize gastrointestinal side effects like nausea or upset stomach.
The dose can be adjusted based on the patient’s blood glucose levels, tolerance, and response to treatment. The maximum dose of Metformin is typically 2000 mg per day, but adjustments may be necessary for each individual.
Side Effects:
Some common side effects of Zita Met Plus may include:
- Gastrointestinal issues (nausea, vomiting, diarrhea, stomach upset) – often with Metformin, though the extended-release formulation may reduce these effects.
- Low blood sugar (hypoglycemia), especially when combined with other anti-diabetic medications (such as insulin or sulfonylureas).
- Lactic acidosis (rare, but serious)—a potential side effect of Metformin, particularly in patients with kidney issues or other risk factors.
- Headache, dizziness, or fatigue.
- Weight loss (common with Metformin use).
- Upper respiratory tract infection or sore throat (may be more common with Teneligliptin).
Precautions:
- Kidney function: Since Metformin is excreted by the kidneys, patients with impaired kidney function should use caution when taking Zita Met Plus. Dosage adjustments or monitoring may be necessary.
- Liver function: Caution is needed in patients with liver problems as both Metformin and Teneligliptin require proper liver function for metabolism.
- Alcohol: Alcohol consumption can increase the risk of lactic acidosis with Metformin and should be limited or avoided.
- Pregnancy and breastfeeding: The safety of Zita Met Plus during pregnancy and breastfeeding has not been established. Consult a healthcare provider before use.
- Hypoglycemia risk: Although Teneligliptin and Metformin do not commonly cause hypoglycemia on their own, the risk increases if taken in combination with other diabetes medications that lower blood sugar.
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