Description
Tenovate-M Cream – 15g Tube
📦 Composition (per gram):
| Ingredient | Strength | Function |
|---|---|---|
| Clobetasol Propionate IP | 0.05% w/w | Super-potent corticosteroid; reduces inflammation |
| Miconazole Nitrate IP | 2.0% w/w | Broad-spectrum antifungal; kills yeast/fungi |
| Chlorocresol IP | 0.1% w/w | Preservative; prevents microbial contamination |
| Base | Non-greasy | Ensures smooth, even topical application |
🎯 Therapeutic Indications / Uses:
Tenovate-M is used for:
-
Fungal skin infections with severe inflammation (e.g., tinea corporis, tinea cruris, tinea pedis)
-
Candidiasis (yeast infections of skin folds)
-
Seborrheic dermatitis
-
Intertrigo (especially if fungal)
-
Inflamed fungal eczema
-
Fungal-infected psoriasis (short-term use)
🟡 This is a dual-action combination: Anti-inflammatory + Antifungal.
⚙️ Mechanism of Action:
| Component | Action |
|---|---|
| Clobetasol Propionate | Suppresses inflammation by inhibiting the release of pro-inflammatory cytokines (via glucocorticoid receptors). |
| Miconazole Nitrate | Disrupts fungal cell membrane by inhibiting ergosterol synthesis, leading to cell death. Effective against Candida, dermatophytes, and Malassezia. |
💊 Dosage & Application:
| Instruction | Details |
|---|---|
| Application frequency | 1–2 times daily, or as directed |
| Apply | Thin layer to affected area |
| Duration | Usually up to 2 weeks, max 4 weeks |
| Avoid | Eyes, mucous membranes, and broken skin |
| Wash hands | Before and after use |
⚠️ Precautions & Warnings:
| ❗ Caution With | 🔍 Why |
|---|---|
| Prolonged use (>2 weeks) | May cause skin thinning, HPA suppression |
| Face, genitals, armpits | Thin skin → more absorption, more side effects |
| Children under 12 | Not recommended unless advised by a doctor |
| Known fungal resistance | Miconazole may not work; confirm diagnosis |
| Occlusive dressings | Can increase systemic absorption |
🧪 Potential Side Effects:
| Local (Common) | Systemic (Rare, prolonged use) |
|---|---|
| Burning, stinging, redness | HPA axis suppression, Cushingoid symptoms |
| Skin atrophy (thinning) | Hyperglycemia, hypertension |
| Stretch marks (striae) | Growth suppression in children |
| Secondary infections | Opportunistic bacterial or fungal growth |
| Contact dermatitis (rare) | Allergy to components like chlorocresol |
🧾 Storage Instructions:
-
Store below 25°C
-
Protect from direct sunlight and moisture
-
Do not freeze
-
Keep out of reach of children
🔁 Alternate Brands (Clobetasol Propionate + Miconazole Nitrate):
| Brand Name | Manufacturer | Pack Size | Remarks |
|---|---|---|---|
| Tenovate-M | GlaxoSmithKline (GSK) | 15g | Trusted brand, dermatology standard |
| Clotic-M | Wallace Pharma | 15g | Popular generic alternative |
| Clomitrin-M | Cipla | 15g | Cost-effective option |
| Clob-GM Plus | Canixa / Generic | 15g | Often combined with gentamicin also |
| Clobmeta-M | Intas | 15g | Available in cream/ointment |
⚠️ Some triple combination creams also include Gentamicin or Ofloxacin along with Clobetasol and Miconazole—ensure correct matching as per infection type.
-
Tenovate-M is a high-potency steroid + antifungal combo for fungal infections with inflammation.
-
Use strictly short-term, only on confirmed fungal conditions.
-
Misuse may cause steroid side effects, fungal resistance, or rebound flares.
-
Not a general-purpose skin cream; avoid for acne, pigmentation, or cosmetic use.
Reviews
There are no reviews yet.