Endogest 200 SR – Strip of 10 Tablets

Description

Endogest 200 SR – Strip of 10 Tablets

Endogest 200 SR is a medication that contains progesterone as its active ingredient. The “SR” in the name indicates that it is a Sustained Release formulation, meaning the medication is released slowly over time, providing a more consistent level of the hormone in the bloodstream.

Active Ingredient:

• Progesterone (200 mg per tablet) – A naturally occurring hormone involved in the regulation of various functions in the body, particularly the menstrual cycle and pregnancy.

Uses of Endogest 200 SR:

Endogest 200 SR is primarily used to address conditions related to hormonal imbalances, particularly in women. It may be prescribed for the following conditions:

1. Hormone Replacement Therapy (HRT):
   • Progesterone is often used as part of hormone replacement therapy in women who have low levels of the hormone, particularly during menopause. It helps balance estrogen effects and reduce the risk of endometrial hyperplasia (thickening of the uterine lining).
2. Support for Early Pregnancy:
   • Endogest can be used in women experiencing threatened miscarriage or early pregnancy support. It helps maintain the uterine lining and supports early pregnancy, especially in cases of progesterone deficiency.
3. Irregular Menstrual Cycles:
   • In cases of anovulatory cycles (where ovulation doesn’t occur) or irregular menstruation, progesterone like Endogest can be prescribed to help regulate the menstrual cycle.
4. Luteal Phase Support in Assisted Reproductive Technology (ART):
   • For women undergoing fertility treatments such as in vitro fertilization (IVF), Endogest can be used to support the luteal phase of the menstrual cycle after ovulation and assist with implantation.
5. Endometrial Hyperplasia Prevention:
   • Progesterone helps prevent the overgrowth of the endometrium (uterine lining), which is a risk when estrogen is taken without progesterone.

How It Works:

• Progesterone is a key hormone in regulating the menstrual cycle and supporting pregnancy. It helps:
  • Prepare the endometrium for implantation of a fertilized egg.
  • Maintain the uterine lining during pregnancy.
  • Regulate the menstrual cycle and prevent excessive uterine bleeding.
  • Balance estrogen effects, particularly in the uterus.

The sustained-release formulation of Endogest 200 SR provides a slow, consistent release of progesterone into the bloodstream, mimicking the body’s natural hormonal fluctuations more closely than immediate-release forms.

Dosage and Administration:

• Typical dosage: The usual dose is 200 mg once daily, typically taken at bedtime to minimize the risk of side effects such as drowsiness or dizziness. The dose may vary based on the specific condition being treated.
  • For fertility treatments, the dose can range from 200 mg to 400 mg per day.
  • For menstrual irregularities, dosages may also vary and are typically taken during the second half of the menstrual cycle.
• Administration: Endogest 200 SR should be swallowed whole with a glass of water. It is usually taken in the evening before bedtime due to its sedative effect, which can help you sleep and reduce daytime fatigue.

Side Effects:

Endogest 200 SR, like all medications, can cause side effects. Some common side effects include:

• Drowsiness or tiredness (due to the sustained-release formulation)
• Headaches
• Nausea
• Breast tenderness
• Mood changes (e.g., irritability or depression)
• Bloating or mild stomach upset
• Dizziness
• Vaginal bleeding or spotting (if used for hormone replacement or menstrual regulation)

Serious side effects (though rare) may include:

• Severe allergic reactions (rash, itching, swelling, or difficulty breathing)
• Chest pain or difficulty breathing (could indicate a serious heart issue)
• Liver problems (yellowing of skin or eyes, dark urine)
• Deep vein thrombosis (DVT) or pulmonary embolism (rare but serious risk for women using hormones)

If you experience any of the above serious symptoms, you should seek medical attention immediately.

Precautions:

Before using Endogest 200 SR, inform your healthcare provider if you have any of the following conditions:

• Allergies: If you are allergic to progesterone or any of the ingredients in the tablet, you should avoid using it.
• History of blood clots: Progesterone can increase the risk of clotting, so it’s important to disclose if you have a history of deep vein thrombosis (DVT), pulmonary embolism, or stroke.
• Liver disease: Progesterone is processed in the liver, so if you have liver issues, your dosage may need to be adjusted or you may need an alternative treatment.
• Heart disease: Those with a history of heart disease should use this medication cautiously, as it can affect blood pressure and heart function.
• Breast cancer or other hormone-sensitive cancers: If you have or have had hormone-sensitive cancers, progesterone may not be appropriate.

Pregnancy and Breastfeeding:

• Pregnancy: Progesterone is naturally present in pregnancy and is often used to support early pregnancy. However, this medication should only be used in pregnancy under the guidance of a healthcare provider, especially in high doses.
• Breastfeeding: Progesterone passes into breast milk in small amounts. It is generally considered safe to use while breastfeeding, but always check with your healthcare provider before using it.

Interactions with Other Drugs:

• Anticonvulsants: Medications like phenytoin or carbamazepine may lower the effectiveness of progesterone.
• Antibiotics: Some antibiotics, particularly rifampin, can also affect how well progesterone works.
• Other hormone treatments: If you’re using other hormone medications, inform your doctor, as there could be interactions or combined side effects.

Storage:

• Store the tablets in a cool, dry place, away from light and moisture. Keep the medication out of the reach of children and do not use it after the expiration date.