Defza 24mg – Tablets 6’s

Description

Defza 24mg is a tablet formulation containing Deflazacort, a corticosteroid medication used to treat various inflammatory and autoimmune conditions due to its anti-inflammatory and immunosuppressive effects.

Composition:

Each tablet of Defza 24mg contains 24 mg of Deflazacort as the active ingredient.

Indications:

Deflazacort is prescribed for the treatment of several conditions that involve inflammation or immune system dysfunction. Some common conditions treated with Defza 24mg include:

• Autoimmune diseases: Such as rheumatoid arthritis, systemic lupus erythematosus, and other inflammatory conditions.
• Inflammatory disorders: Conditions like inflammatory bowel disease (IBD), dermatitis, and vasculitis.
• Severe allergic reactions: Such as exacerbations of asthma or anaphylaxis.
• Muscle wasting diseases: For example, Duchenne muscular dystrophy.
• Organ inflammation: Conditions like nephrotic syndrome (kidney inflammation) or inflammation in other organs.

Mechanism of Action:

Deflazacort works by:

• Reducing inflammation: It decreases the production of pro-inflammatory substances, such as prostaglandins.
• Suppressing the immune system: It helps control autoimmune diseases by reducing immune system activity, which is useful in preventing the immune system from attacking healthy tissues.

Dosage:

The appropriate dosage of Defza 24mg will depend on the condition being treated, the severity of the condition, and the patient’s weight. A typical dosage regimen may include:

• For adults, the usual starting dose is typically 0.1 to 0.3 mg per kg body weight per day.
• For children, the dosage is adjusted based on the child’s weight and the specific condition being treated.

Defza 24mg is typically taken once a day, often in the morning, to minimize the risk of insomnia. It should be taken with food to minimize gastrointestinal side effects.

Side Effects:

Like all corticosteroids, Defza 24mg can cause a range of side effects, especially with long-term use. Some potential side effects include:

• Weight gain (due to fluid retention and increased appetite)
• Increased blood pressure
• Elevated blood sugar levels (hyperglycemia), which may worsen diabetes
• Gastrointestinal issues (e.g., ulcers, indigestion)
• Osteoporosis (bone thinning, especially with long-term use)
• Mood changes (e.g., irritability, anxiety, or depression)
• Increased risk of infections due to immune suppression
• Cataracts or glaucoma (eye problems, particularly with prolonged use)

Precautions:

• Tapering: Long-term use of Defza 24mg requires careful tapering. The dose should not be stopped abruptly; it should be reduced gradually to avoid withdrawal symptoms and adrenal insufficiency.
• Infection risk: Deflazacort suppresses the immune system, making you more susceptible to infections. If you develop any symptoms of infection, it is important to contact your healthcare provider immediately.
• Bone health: Prolonged corticosteroid use can lead to bone thinning, so you may need calcium and vitamin D supplementation, along with monitoring of bone density.
• Diabetes: If you have diabetes, your blood sugar levels should be monitored regularly, as corticosteroids can increase blood glucose levels.
• Pregnancy and breastfeeding: Defza 24mg should be used during pregnancy only if clearly needed. It is excreted in breast milk, so breastfeeding mothers should consult with a healthcare provider before using this medication.

Administration:

• Defza 24mg tablets are typically taken once daily, preferably in the morning.
• The tablet should be taken with food to minimize gastrointestinal discomfort.
• Swallow the tablet whole without crushing or chewing it.