Description

Amtas-M-50 – Strip of 15 Tablets

Amtas-M-50 is a combination medication that contains Metoprolol Succinate and Amlodipine Besylate. It is commonly prescribed for managing hypertension (high blood pressure) and angina (chest pain).

Composition of Amtas-M-50:

• Metoprolol Succinate (47.5 mg), which is equivalent to Metoprolol Tartrate 50 mg (as prolonged release): Metoprolol is a beta-blocker that works by blocking the effects of adrenaline on the heart, reducing heart rate, blood pressure, and the heart’s workload. The prolonged-release form allows for steady delivery of the drug throughout the day.
• Amlodipine Besylate (5 mg): A calcium channel blocker that works by relaxing and widening the blood vessels, which helps lower blood pressure and improve blood flow to the heart.

Uses of Amtas-M-50 (Metoprolol + Amlodipine):

1. Hypertension (High Blood Pressure): This combination helps lower blood pressure through two mechanisms: Metoprolol reduces heart rate and workload on the heart, while Amlodipine relaxes blood vessels, further aiding in blood pressure control.
2. Angina (Chest Pain): Amlodipine helps prevent chest pain by improving blood flow to the heart, while Metoprolol reduces the oxygen demand of the heart, preventing angina attacks.
3. Heart Failure: Metoprolol is beneficial in treating heart failure, improving heart function and reducing symptoms by slowing the heart rate and decreasing the heart’s workload.
4. Post-Heart Attack Recovery: Metoprolol is commonly prescribed after a heart attack to reduce the risk of further complications and improve heart function.

Benefits of the Combination:

• Amlodipine helps to dilate blood vessels and lower blood pressure, which eases the strain on the heart.
• Metoprolol helps slow the heart rate and reduces the heart’s demand for oxygen, which is helpful in managing both high blood pressure and chest pain.
• Prolonged-release formulation of Metoprolol ensures consistent, effective blood pressure control over 24 hours.

Common Side Effects:

• Swelling of the ankles or feet (due to Amlodipine)
• Dizziness or lightheadedness, especially when standing up quickly
• Fatigue or tiredness (from Metoprolol)
• Slow heart rate (bradycardia) (due to Metoprolol)
• Cold hands or feet (from Metoprolol)
• Headache or flushing (from Amlodipine)
• Nausea or upset stomach
• Shortness of breath (in rare cases, related to Metoprolol)

Precautions:

• Heart Conditions: Metoprolol should be used with caution in patients with heart conditions like heart failure, bradycardia (slow heart rate), or atrioventricular (AV) block.
• Kidney or Liver Disease: Both Metoprolol and Amlodipine may require dose adjustments in patients with kidney or liver disease.
• Asthma or Respiratory Issues: Beta-blockers like Metoprolol may worsen asthma or cause bronchospasm, so they should be used cautiously in patients with respiratory conditions.
• Pregnancy: Consult your doctor before using this medication during pregnancy, as Metoprolol should be used with caution in pregnant women.
• Alcohol: Alcohol can increase the risk of side effects, such as dizziness or low blood pressure, so it should be consumed with caution.

Dosage:

• The usual starting dose of Amtas-M-50 is one tablet (Metoprolol 47.5 mg + Amlodipine 5 mg) once daily. The dose may be adjusted based on your condition and response to the treatment.
• Packaging: The medication is commonly available in a strip of 15 tablets, which may be prescribed for a 15-day treatment cycle or longer, depending on the prescribed dosage.

Important Notes:

• Regular Monitoring: Patients using Amtas-M-50 should have their blood pressure, heart rate, and kidney function monitored regularly to ensure the medication is working effectively and to avoid potential side effects.
• Diet and Lifestyle: A low-sodium diet, weight management, and regular physical activity are important for controlling high blood pressure and improving overall heart health.
• Sudden Discontinuation: Do not suddenly stop taking Metoprolol, as doing so can lead to a rebound increase in blood pressure and heart rate. Always consult your doctor before making any changes to your medication regimen.

Always follow your healthcare provider’s instructions regarding the proper use of Amtas-M-50. If you experience any unusual symptoms or side effects, contact your doctor immediately.