Amlodac M is a combination medication that contains Metoprolol and Amlodipine. This medication is typically prescribed for managing high blood pressure (hypertension) and angina (chest pain).

Composition of Amlodac M:

• Metoprolol Succinate (47.5 mg), equivalent to Metoprolol Tartrate (50 mg) (as prolonged release):
  Metoprolol is a beta-blocker that works by blocking beta receptors in the heart, which reduces the heart rate, the force of heart contractions, and lowers blood pressure. This helps reduce the workload on the heart and is effective in preventing heart attacks, treating angina, and managing hypertension.
• Amlodipine Besylate (5 mg), equivalent to Amlodipine:
  Amlodipine is a calcium channel blocker that works by relaxing and widening the blood vessels, allowing blood to flow more easily and reducing blood pressure. It also helps to relieve chest pain (angina) by improving blood flow to the heart.

Uses of Amlodac M (Metoprolol 50 mg + Amlodipine 5 mg):

1. Hypertension (High Blood Pressure):
   The combination of Metoprolol and Amlodipine helps lower blood pressure by reducing the force of the heart’s contractions (Metoprolol) and relaxing the blood vessels (Amlodipine). This makes it easier for the heart to pump blood and reduces the overall strain on the heart.
2. Angina (Chest Pain):
   Amlodipine improves blood flow to the heart, helping to prevent chest pain (angina) by reducing the heart’s oxygen demand and relieving stress on the heart muscle. Metoprolol helps prevent episodes of chest pain by controlling heart rate and reducing the heart’s workload.
3. Heart Failure:
   In some cases, Amlodac M is used as part of the treatment for heart failure, as it helps to lower blood pressure and reduces the heart’s workload. Metoprolol in particular has a beneficial effect on heart failure by controlling the heart rate and improving heart function.
4. Post-Heart Attack Care:
   Metoprolol is commonly used after a heart attack to prevent further damage to the heart and reduce the risk of another heart attack. The combination with Amlodipine helps by reducing blood pressure and improving overall circulation.

Benefits of Amlodac M:

• Dual Action: The combination of Metoprolol (beta-blocker) and Amlodipine (calcium channel blocker) provides comprehensive management of hypertension and angina.
• Prolonged Release: The extended-release form of Metoprolol (Metoprolol Succinate) provides steady, long-lasting effects, reducing the need for multiple daily doses and helping maintain consistent control of heart rate and blood pressure.
• Reduced Risk of Cardiovascular Events: This medication lowers the risk of heart attacks, strokes, and other cardiovascular complications by controlling blood pressure and improving blood flow to the heart.

Common Side Effects:

• Dizziness or lightheadedness, especially when standing up quickly (due to lower blood pressure).
• Fatigue or tiredness.
• Swelling (edema), especially in the lower legs or ankles (common with Amlodipine).
• Slow heart rate (bradycardia) (due to Metoprolol).
• Headache.
• Shortness of breath (rare, but possible with beta-blockers).
• Nausea or mild stomach discomfort.
• Flushing or warmth, particularly in the face.

Precautions:

• Heart Conditions:
  Amlodac M should be used cautiously in patients with certain heart conditions such as bradycardia (slow heart rate), heart block, or severe heart failure. Metoprolol can further lower the heart rate, so monitoring is important.
• Liver or Kidney Problems:
  Both Metoprolol and Amlodipine are metabolized by the liver, so the medication should be used with caution in patients with liver disease. Kidney function should be monitored, especially if there is a history of kidney issues.
• Breathing Issues:
  Metoprolol can exacerbate breathing problems in people with asthma or chronic obstructive pulmonary disease (COPD). Care should be taken, and alternative medications may be considered if breathing issues are present.
• Pregnancy and Breastfeeding:
  If pregnant or breastfeeding, consult your healthcare provider before using Amlodac M, as both Metoprolol and Amlodipine may have effects on the baby. Metoprolol is classified as Category C (risk cannot be ruled out) during pregnancy.
• Diabetes:
  Metoprolol can mask some symptoms of low blood sugar (hypoglycemia), such as increased heart rate. People with diabetes need to monitor their blood sugar closely when on beta-blockers like Metoprolol.
• Alcohol:
  Alcohol can enhance the blood pressure-lowering effects of Amlodac M, leading to dizziness or fainting. It should be consumed cautiously while on this medication.

Dosage:

• The typical dose of Amlodac M is one tablet (Metoprolol 50 mg + Amlodipine 5 mg) once daily. However, the dose may vary based on the patient’s condition and response to the medication.
• Packaging: It is commonly available in a strip of 15 tablets, typically providing a 15-day supply at one tablet per day.

Important Notes:

• Regular Monitoring: While on Amlodac M, it is important to monitor blood pressure, heart rate, and kidney function regularly to ensure that the medication is working as intended and to detect any potential side effects.
• Lifestyle Changes: Along with medication, adopting a healthy lifestyle—including a balanced diet, regular exercise, and stress management—will help control blood pressure and improve heart health.

Always follow your healthcare provider’s instructions when using Amlodac M. If you experience any side effects or unusual symptoms, contact your doctor immediately.