Description
Vildee-M 500 Tablet
Vildee-M 500 Tablet is an oral anti-diabetic medicine used for the treatment of Type 2 Diabetes Mellitus. It contains two active medicines:
- Vildagliptin 50 mg
- Metformin Hydrochloride 500 mg
This combination helps control blood sugar levels effectively when diet, exercise, and single-drug therapy are not sufficient.
The medicine is commonly prescribed to adults with uncontrolled blood glucose levels and helps reduce the risk of complications related to diabetes such as kidney disease, nerve damage, eye problems, and cardiovascular disorders.
Composition
Active Ingredients
A. Vildagliptin – 50 mg
Vildagliptin belongs to the DPP-4 inhibitor class of medicines.
Mechanism of Action
- Increases incretin hormone levels
- Enhances insulin release after meals
- Decreases glucagon secretion
- Helps maintain better blood glucose control
B. Metformin Hydrochloride – 500 mg
Metformin belongs to the biguanide class.
Mechanism of Action
- Reduces glucose production in the liver
- Improves insulin sensitivity
- Reduces intestinal glucose absorption
- Helps lower fasting and post-meal sugar levels
Therapeutic Class
- Anti-diabetic medicine
- Oral hypoglycemic agent
- DPP-4 inhibitor + Biguanide combination
Indications
Vildee-M 500 is prescribed for:
Primary Uses
- Type 2 Diabetes Mellitus
- Uncontrolled blood sugar
- Combination diabetic therapy
- Post-meal glucose control
- Insulin resistance management
Secondary Benefits
- Helps improve HbA1c levels
- Reduces diabetic complications risk
- Supports long-term glucose management
How the Medicine Works
The combination of Vildagliptin and Metformin works together through complementary mechanisms.
Vildagliptin Actions
- Stimulates insulin secretion only when glucose is elevated
- Reduces excess glucagon production
- Improves pancreatic beta-cell response
Metformin Actions
- Reduces hepatic glucose production
- Improves peripheral glucose utilization
- Enhances insulin sensitivity
Combined Effect
- Better fasting sugar control
- Better postprandial sugar control
- Lower HbA1c
- Reduced risk of hypoglycemia compared to some older diabetic medicines
Dosage Information
Available Strengths
Vildee-M may be available in different strengths such as:
- 500 mg + 50 mg
- 850 mg + 50 mg
- 1000 mg + 50 mg
Usual Adult Dose
The dosage depends on:
- Blood sugar levels
- Previous medications
- Kidney function
- Doctor’s advice
General Administration Instructions
- Take after meals
- Swallow whole with water
- Do not crush or chew unless advised
- Take regularly at the same time daily
Missed Dose
If you miss a dose:
- Take it as soon as remembered
- Skip if it is almost time for the next dose
- Never double the dose
Overdose
Overdose symptoms may include:
- Severe weakness
- Vomiting
- Low blood sugar
- Breathing difficulty
- Lactic acidosis symptoms
Seek immediate medical attention in suspected overdose.
Side Effects
Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal discomfort
- Headache
- Dizziness
- Weakness
- Metallic taste
- Gas or bloating
Less Common Side Effects
- Skin rash
- Joint pain
- Reduced appetite
- Tremors
Serious Side Effects
A. Lactic Acidosis
Rare but serious condition associated with Metformin.
Symptoms
- Muscle pain
- Extreme weakness
- Fast breathing
- Cold hands and feet
- Severe fatigue
B. Pancreatitis
Possible with Vildagliptin.
Symptoms
- Severe abdominal pain
- Vomiting
- Back pain
C. Liver Problems
- Yellow eyes
- Dark urine
- Persistent nausea
Contraindications
Do not use Vildee-M in:
- Severe kidney disease
- Severe liver disease
- Diabetic ketoacidosis
- Type 1 Diabetes
- Severe dehydration
- Hypersensitivity to ingredients
Warnings and Precautions
Kidney Monitoring
Regular kidney function tests are important.
Liver Monitoring
Liver enzymes should be checked periodically.
Elderly Patients
Use carefully in elderly individuals due to higher risk of kidney impairment.
Alcohol Consumption
Avoid excessive alcohol because it increases risk of lactic acidosis.
Surgery and Contrast Dye
Temporary discontinuation may be required before:
- Major surgery
- CT scan with contrast dye
Drug Interactions
Medicines That May Interact
Anti-diabetic Medicines
- Insulin
- Sulfonylureas
Blood Pressure Medicines
- ACE inhibitors
- Diuretics
Steroids
Can increase blood sugar levels.
Alcohol
May increase lactic acidosis risk.
Contrast Media
Can affect kidney function.
Use in Special Populations
Pregnancy
Use only if clearly advised by a doctor.
Breastfeeding
Consult healthcare provider before use.
Children
Safety may vary depending on age and clinical guidelines.
Elderly
Careful monitoring is required.
Monitoring Parameters
Patients taking Vildee-M should monitor:
- Fasting blood sugar
- Postprandial blood sugar
- HbA1c
- Kidney function
- Liver function
- Body weight
Diet Recommendations
Recommended Foods
- Whole grains
- Vegetables
- High-fiber foods
- Lean proteins
- Fresh fruits in moderation
Foods to Limit
- Sugary drinks
- White bread
- Excess sweets
- Fried foods
- Alcohol
Exercise Recommendations
Regular physical activity improves insulin sensitivity.
Recommended Activities
- Walking
- Cycling
- Yoga
- Light jogging
- Stretching
Aim for at least 30 minutes daily.
Blood Sugar Targets
Typical diabetic goals may include:
- Fasting sugar: 80–130 mg/dL
- Post-meal sugar: below 180 mg/dL
- HbA1c: below 7%
Targets vary according to patient condition.
Symptoms of High Blood Sugar
Hyperglycemia Symptoms
- Excess thirst
- Frequent urination
- Blurred vision
- Fatigue
- Weight loss
Symptoms of Low Blood Sugar
Although risk is lower, hypoglycemia may occur.
Symptoms
- Sweating
- Trembling
- Hunger
- Fast heartbeat
- Dizziness
- Confusion
Quick Treatment
- Glucose tablets
- Fruit juice
- Sugar candy
Lifestyle Advice for Diabetes
Important Measures
- Maintain healthy weight
- Exercise regularly
- Monitor blood sugar
- Follow medication schedule
- Avoid smoking
- Limit alcohol
- Get regular checkups
Storage Instructions
- Store below room temperature
- Protect from moisture
- Keep away from direct sunlight
- Keep out of reach of children
Packaging Information
Commonly available as:
- Strip of 10 tablets
- Strip of 15 tablets
Packaging may vary by manufacturer.
Manufacturer Information
Different pharmaceutical companies may manufacture similar combinations under various brand names.
Advantages of Combination Therapy
Benefits
- Better glucose control
- Reduced pill burden
- Improved patient compliance
- Complementary mechanism of action
Disadvantages
Possible Limitations
- Gastrointestinal side effects
- Need for regular monitoring
- Not suitable for severe kidney disease
Comparison with Other Diabetes Medicines
| Medicine Type | Risk of Hypoglycemia | Weight Effect |
|---|---|---|
| Metformin + Vildagliptin | Low | Neutral |
| Sulfonylureas | Higher | Weight gain |
| Insulin | Moderate to High | Weight gain |
| SGLT2 inhibitors | Low | Weight loss |
Frequently Asked Questions
Q1. Is Vildee-M used for Type 1 Diabetes?
No. It is mainly used for Type 2 Diabetes Mellitus.
Q2. Can it be taken on an empty stomach?
Usually recommended after meals.
Q3. Does it cause weight gain?
Generally weight neutral.
Q4. Can alcohol be consumed?
Avoid excessive alcohol intake.
Q5. Can diabetic patients exercise while taking it?
Yes, exercise is strongly recommended.
Importance of HbA1c Monitoring
HbA1c reflects average blood sugar over approximately 3 months.
Importance
- Assesses long-term control
- Helps adjust therapy
- Predicts complications risk
Diabetic Complications Prevented by Good Sugar Control
Eye Complications
- Diabetic retinopathy
Kidney Complications
- Diabetic nephropathy
Nerve Damage
- Neuropathy
Heart Disease
- Heart attack
- Stroke
Importance of Regular Medical Follow-Up
Patients should visit doctors regularly for:
- Blood sugar review
- Dose adjustment
- Kidney tests
- Liver tests
- Blood pressure monitoring
- Foot examination
Signs That Need Immediate Medical Attention
Seek urgent medical care if you experience:
- Severe abdominal pain
- Breathing difficulty
- Chest pain
- Fainting
- Severe weakness
- Persistent vomiting
Diabetic Foot Care
Daily Foot Care Tips
- Inspect feet daily
- Keep feet clean and dry
- Wear proper footwear
- Avoid walking barefoot
Long-Term Diabetes Management
Effective diabetes management requires:
- Medication adherence
- Healthy eating
- Regular exercise
- Weight control
- Regular checkups
General Safety Advice
- Never stop medicine suddenly without medical advice
- Keep emergency glucose available
- Inform doctors about all medications being taken
- Carry diabetic identification if possible
Vildee-M 500 Tablet combines Vildagliptin 50 mg and Metformin 500 mg to provide effective blood sugar control in Type 2 Diabetes Mellitus. The medicine works through multiple mechanisms to improve insulin activity and reduce excess glucose production.
When used correctly along with proper diet, exercise, and regular monitoring, it helps reduce diabetic complications and improves overall metabolic control.
Patients should follow doctor recommendations carefully and attend regular follow-up visits for safe and effective treatment.
This document is for educational purposes only and should not replace professional medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.
Reviews
There are no reviews yet.