Rabesec 20 Tablet (cipla)

Description

Rabesec 20 Tablet is another medication produced by Cipla Ltd. It contains Rabeprazole, a proton pump inhibitor (PPI), and is primarily used to reduce stomach acid production. Here’s a detailed look at the medication:

Composition:

• Rabeprazole (20 mg) – The active ingredient. Rabeprazole works by inhibiting the proton pump in the stomach, which reduces gastric acid secretion.

Mechanism of Action:

Rabeprazole blocks the proton pump (H+/K+ ATPase) in the parietal cells of the stomach, reducing the amount of acid produced. This helps in treating conditions related to excess acid production in the stomach, such as heartburn, acid reflux, and ulcers.

Indications:

• Gastroesophageal Reflux Disease (GERD): To treat symptoms of GERD, including heartburn and acid regurgitation.
• Peptic Ulcers: Helps in healing peptic ulcers by reducing stomach acid that irritates the ulcerated area.
• Helicobacter pylori eradication therapy: In combination with antibiotics, Rabesec 20 Tablet is used to treat H. pylori infection, which is often associated with peptic ulcers.
• Zollinger-Ellison Syndrome: A condition where the stomach produces excessive acid due to tumors in the pancreas or duodenum.
• Gastritis and Duodenitis: It can also be used to reduce inflammation in the stomach lining caused by excessive acid production.

Dosage:

• The usual dose for Rabeprazole 20 mg is one tablet per day, preferably in the morning before food.
• For GERD: 20 mg once daily for up to 4-8 weeks.
• For peptic ulcers: 20 mg once daily for up to 4-6 weeks.
• The dosage may be adjusted depending on the specific condition and the patient’s response.

Important: Always follow the prescribed dosage from your healthcare provider and do not exceed the recommended dose.

Side Effects:

While Rabeprazole is generally well-tolerated, some potential side effects include:

• Common Side Effects:
  • Headache
  • Nausea or vomiting
  • Diarrhea or constipation
  • Abdominal pain or discomfort
  • Flatulence (gas)
• Less common but more serious side effects:
  • Severe allergic reactions (e.g., rash, itching, swelling, dizziness)
  • Liver function abnormalities
  • Bone fractures (with long-term use)
  • Low magnesium levels (which may lead to muscle cramps, seizures, and irregular heartbeats)

If any serious side effects occur, it is important to contact a healthcare provider immediately.

Precautions:

• Pregnancy and Breastfeeding: Rabeprazole should be used during pregnancy only if the potential benefit justifies the risk to the fetus. It is excreted in breast milk, so breastfeeding mothers should consult their doctor before using this medication.
• Kidney or Liver Issues: Caution should be exercised in patients with impaired liver function, and dose adjustments may be needed.
• Long-term Use: Prolonged use of PPIs, including rabeprazole, has been associated with an increased risk of bone fractures, kidney disease, and certain gastrointestinal infections. Regular monitoring may be required during long-term treatment.

Interactions:

• Drugs that increase stomach pH (e.g., antacids, H2 blockers): May reduce the effectiveness of rabeprazole.
• Clopidogrel (blood thinner): Rabeprazole may reduce the effectiveness of clopidogrel, a medication used to prevent blood clots.
• Methotrexate: Rabeprazole can increase the blood levels of methotrexate, leading to potential toxicity.