Duphalac Syrup – Complete Details

Composition:

• Lactulose Solution U.S.P.
  (A synthetic disaccharide laxative)

Overview

Duphalac 450 ml is a well-known lactulose-based laxative syrup used to treat constipation and to manage hepatic encephalopathy (a liver-related condition caused by high ammonia levels). It works gently on the colon by increasing water content in the stool, making bowel movements easier and more regular.

Duphalac is safe for use in children, adults, and elderly patients, including pregnant or breastfeeding women when prescribed by a doctor.

How Duphalac Works

1. Relieves Constipation (Osmotic Laxative)

• Lactulose passes unchanged to the large intestine.

• Intestinal bacteria break it down into mild organic acids.

• These acids draw water into the colon.

• Stools become softer and easier to pass.

• Helps restore normal bowel rhythm.

2. Reduces Ammonia Levels (For Liver Patients)

• Converts ammonia (NH₃) to ammonium (NH₄⁺), which cannot be absorbed.

• Helps remove ammonia through stool.

• Prevents confusion, drowsiness, or disorientation seen in hepatic encephalopathy.

Indications / Uses

• Chronic constipation

• Hard stools / painful defecation

• Anal fissures / hemorrhoids (makes stool softer)

• Hepatic encephalopathy

• Maintaining regular bowel movement

Benefits

• Gentle yet effective laxative

• Non-habit forming

• Safe for long-term use under supervision

• Helps prevent complications in liver disease

• Works naturally and maintains gut health

Dosage (General Guidance)

(Exact dose must be taken as per doctor’s advice)

• Adults: Usually 15–30 ml daily

• Children: Dose depends on age

• Hepatic encephalopathy: Higher doses as advised

How To Use

1. Measure dose using the measuring cup.

2. Take directly or mix with water/juice.

3. Drink plenty of water.

4. Effect starts in 24–48 hours.

Side Effects

Common and mild:

• Gas / bloating

• Abdominal cramps

• Nausea

• Loose stools (if dose is high)

These usually decrease as the body adjusts.

Precautions

• Use cautiously in diabetics (contains sugar).

• Avoid if you have intestinal obstruction.

• Do not take large doses without supervision.

• For children, use only as advised by a doctor.

• Inform doctor if no improvement within a few days.

Storage

• Store at room temperature.

• Keep bottle tightly capped.

• Protect from direct sunlight.

• Keep away from children.