Description

Defza 6 – Strip of 10 Tablets

Defza 6mg is a tablet formulation containing Deflazacort, a corticosteroid medication used primarily for its anti-inflammatory and immunosuppressive effects.

Composition:

Each tablet of Defza 6mg contains 6 mg of Deflazacort as the active ingredient.

Indications:

Deflazacort is prescribed for a variety of conditions that involve inflammation or immune system dysfunction. Some of the common conditions treated with Defza 6mg include:

• Autoimmune diseases: Such as rheumatoid arthritis, systemic lupus erythematosus, and other inflammatory conditions.
• Inflammatory conditions: Such as inflammatory bowel disease (IBD), dermatitis, and vasculitis.
• Severe allergic reactions: Including exacerbations of asthma or anaphylaxis.
• Muscle wasting diseases: Such as Duchenne muscular dystrophy.
• Organ inflammation: For example, nephrotic syndrome (kidney inflammation) or inflammation affecting other organs.

Mechanism of Action:

Deflazacort, like other corticosteroids, works by:

• Reducing inflammation: It inhibits the production of substances (e.g., prostaglandins) that cause inflammation.
• Suppressing the immune system: It reduces immune system activity, which helps treat autoimmune diseases where the body’s immune system attacks healthy tissue.

Dosage:

The appropriate dosage of Defza 6mg depends on the condition being treated, the patient’s weight, and the severity of the condition. Generally:

• For adults, the starting dose typically ranges from 0.1 to 0.3 mg per kg body weight per day.
• For children, the dosage is adjusted based on weight and the specific condition being treated.

Defza 6mg is typically taken once daily, usually in the morning. It should be taken with food to minimize gastrointestinal side effects.

Side Effects:

Like other corticosteroids, Defza 6mg can cause a variety of side effects, particularly when used for prolonged periods. Some potential side effects include:

• Weight gain (due to fluid retention and increased appetite)
• Increased blood pressure
• Elevated blood sugar levels (hyperglycemia), which may worsen diabetes
• Gastrointestinal discomfort (e.g., stomach ulcers, indigestion)
• Osteoporosis (bone thinning with long-term use)
• Mood changes (e.g., irritability, anxiety, or depression)
• Increased susceptibility to infections due to immune suppression
• Cataracts or glaucoma (eye issues with prolonged use)

Precautions:

• Tapering: Corticosteroids like Defza 6mg should not be stopped suddenly, particularly if taken for a long period. A gradual reduction (tapering) of the dose is necessary to avoid withdrawal symptoms and adrenal insufficiency.
• Infection Risk: Deflazacort can suppress the immune system, so patients should avoid exposure to infections. Any signs of infection should be reported to a healthcare provider promptly.
• Bone Health: Long-term use can lead to bone thinning (osteoporosis), so calcium and vitamin D supplements may be recommended, and bone density monitoring may be necessary.
• Diabetes: Regular monitoring of blood glucose levels is important for patients with diabetes, as corticosteroids can elevate blood sugar levels.
• Pregnancy and Breastfeeding: Deflazacort should be used during pregnancy only if clearly needed, and breastfeeding mothers should consult with their healthcare provider before using this medication, as it can pass into breast milk.

Administration:

• Defza 6mg tablets should be taken as prescribed, usually once a day, preferably in the morning.
• The tablet should be taken with food to minimize the risk of gastrointestinal discomfort.
• Swallow the tablet whole without crushing or chewing it.