Description
Amtas-M-25 is a combination medication that contains Metoprolol Succinate and Amlodipine Besylate as the active ingredients. This combination is used primarily for managing high blood pressure (hypertension) and certain types of angina (chest pain).
Composition of Amtas-M-25:
- Metoprolol Succinate (23.75 mg): This is the sustained-release form of Metoprolol, a beta-blocker. It is equivalent to 25 mg of Metoprolol Tartrate. Metoprolol works by blocking certain receptors (beta-1 receptors) in the heart, helping to reduce heart rate and blood pressure. The extended-release formulation allows for a steady release of the medication over time, providing longer-lasting effects.
- Amlodipine Besylate (5 mg): A calcium channel blocker, Amlodipine helps relax the blood vessels, making it easier for the heart to pump blood and lowering blood pressure. It also helps to prevent chest pain (angina).
Uses of Amtas-M-25 (Metoprolol + Amlodipine):
- Hypertension (High Blood Pressure): This combination medication helps lower blood pressure. Metoprolol reduces the heart rate and workload on the heart, while Amlodipine relaxes and widens the blood vessels.
- Angina (Chest Pain): Amlodipine improves blood flow to the heart, while Metoprolol helps reduce the heart’s oxygen demand by lowering the heart rate. Together, they help prevent chest pain.
- Heart Disease: Metoprolol is used in the management of heart conditions like heart failure or post-heart attack recovery by reducing the strain on the heart.
Benefits of the Combination:
- Metoprolol: By reducing the heart rate, Metoprolol helps to manage blood pressure, decrease the risk of heart attacks, and prevent chest pain.
- Amlodipine: It helps to lower blood pressure and prevent angina by dilating the blood vessels, improving blood flow, and reducing the heart’s workload.
- The extended-release form of Metoprolol ensures a steady, controlled effect throughout the day, improving patient adherence to the medication.
Common Side Effects:
- Fatigue or tiredness
- Dizziness or lightheadedness, especially when standing up quickly
- Swelling in the ankles or feet (due to Amlodipine)
- Slow heart rate (bradycardia) or feeling faint (from Metoprolol)
- Headache or flushing (from Amlodipine)
- Shortness of breath, especially in those with heart failure
- Cold hands or feet (from Metoprolol)
Precautions:
- Heart Conditions: Metoprolol should be used with caution in patients with heart failure, bradycardia, or other heart conditions.
- Liver or Kidney Disease: Dose adjustments may be necessary for patients with liver or kidney problems.
- Asthma or Respiratory Issues: Beta-blockers like Metoprolol can worsen asthma or bronchospasm, so they should be used cautiously in these patients.
- Pregnancy and Breastfeeding: Consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
- Discontinuation: Do not suddenly stop taking this medication, especially Metoprolol, as this can lead to a sudden increase in blood pressure or heart rate. The dosage should be reduced gradually under a doctor’s guidance.
Dosage:
- Amtas-M-25 is typically prescribed as one tablet (Metoprolol 25 mg and Amlodipine 5 mg) once daily, depending on the patient’s condition and response to treatment. The medication is usually taken as a sustained-release tablet, so it should not be crushed or chewed.
- Packaging: This medication typically comes in a strip of 15 tablets, often prescribed for a 15-day treatment cycle or as part of an ongoing regimen.
Important Notes:
- Regular Monitoring: Patients taking this medication should have their blood pressure, heart rate, and overall cardiovascular health monitored regularly.
- Alcohol: Limit alcohol consumption as it may increase the risk of side effects like dizziness or low blood pressure.
Always follow your healthcare provider’s instructions regarding the proper use of Amtas-M-25. If you experience any unusual symptoms or side effects, contact your doctor immediately.
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