Description
Alcarex – Bottle of 5 ml Drops
Ocupol – Bottle of 5 ml Eye/Ear Drops
Type: Combination antibiotic eye/ear drop
Form: Sterile ophthalmic/otic solution
Pack Size: 5 ml bottle
Route: For external use only – either in eyes or ears
✅ Composition (per ml):
| Ingredient | Strength | Function |
|---|---|---|
| Polymyxin B Sulphate BP | 5000 IU | Bactericidal against Gram-negative bacteria (e.g., Pseudomonas, E. coli) |
| Chloramphenicol IP | 4 mg | Broad-spectrum bacteriostatic antibiotic |
| Phenylmercuric Nitrate IP | 0.001% w/v | Preservative with weak antimicrobial properties |
| Sterile base | q.s. | Vehicle (solvent) |
💊 Therapeutic Uses:
👁️ As Eye Drops:
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Bacterial conjunctivitis
-
Blepharitis (eyelid inflammation)
-
Keratitis (non-viral)
-
Post-surgical eye infections
👂 As Ear Drops:
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Otitis externa (outer ear infection)
-
Ear discharge due to bacterial infection (if eardrum is intact)
💡 Always use under medical supervision, especially for eye conditions.
⚙️ Mechanism of Action:
-
Chloramphenicol inhibits bacterial protein synthesis
-
Polymyxin B disrupts bacterial cell membranes
→ Together they act synergistically against a broad spectrum of bacteria
🧴 Dosage (Typical):
👁️ Eyes:
-
1–2 drops into the affected eye(s), every 4–6 hours, or as prescribed
👂 Ears:
-
2–3 drops into the affected ear(s), 2–3 times daily
Shake well before use and wash hands before application.
⚠️ Precautions:
-
Do not use in viral or fungal infections
-
Do not use while wearing contact lenses
-
Prolonged use may lead to superinfections (like fungal growth)
-
Use with caution in children and pregnant women
-
May cause hypersensitivity reactions
❌ Contraindications:
-
Allergy to Chloramphenicol, Polymyxin B, or mercurial preservatives
-
Patients with blood disorders (aplastic anemia risk with long-term chloramphenicol use)
🔄 Common Side Effects:
| Side Effect | Description |
|---|---|
| Mild burning/stinging | Usually temporary |
| Redness or irritation | If persistent, discontinue use |
| Blurred vision (temporary) | After application (eyes only) |
| Rare: allergic reaction | Rash, swelling, itching, or discomfort |
🧊 Storage:
-
Store in a cool, dry place below 25°C
-
Protect from light
-
Use within 30 days of opening
🛑 Important:
-
Do not self-medicate in eye/ear infections
-
Do not use in viral conditions (e.g., viral conjunctivitis or herpes simplex eye infections)
-
Seek medical evaluation if there’s no improvement in 48–72 hours
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-
Application instructions for safe use?
-
A comparison with Oflacin drops?
-
A list of alternative combination antibiotic drops?
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Here are the complete details for:
Alcarex – Bottle of 5 ml Eye Drops
Category: Anti-allergic ophthalmic drops
Form: Sterile ophthalmic solution
Pack Size: 5 ml bottle
Route: For external use in eyes only
✅ Composition (per ml):
| Ingredient | Strength | Role |
|---|---|---|
| Alcaftadine | 0.25% w/v | Antihistamine (H1 receptor antagonist) |
| Excipients | q.s. | Sterile aqueous base |
💊 Therapeutic Uses:
Alcarex is primarily used for the prevention and treatment of allergic eye conditions, such as:
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Allergic conjunctivitis
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Seasonal allergic conjunctivitis (SAC) (e.g., due to pollen, dust)
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Perennial allergic conjunctivitis (PAC) (year-round allergens like pet dander, mold)
⚙️ Mechanism of Action:
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Alcaftadine is a selective H1 histamine receptor antagonist
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It also stabilizes mast cells, preventing histamine release
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Reduces itching, redness, watering, and swelling of the eyes
🧴 Dosage (Typical):
-
Adults and children ≥2 years:
1 drop in each affected eye once daily (or as prescribed)
Relief is usually rapid, often within minutes of instillation.
⚠️ Precautions:
-
For topical ophthalmic use only
-
Do not touch the dropper tip to any surface (risk of contamination)
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Not recommended for children under 2 years
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Use with caution in pregnancy or breastfeeding (consult doctor)
-
Remove contact lenses before use, wait at least 10 minutes before reinserting
❌ Side Effects (Rare or Mild):
| Side Effect | Description |
|---|---|
| Eye irritation/burning | Usually temporary |
| Headache | Mild, infrequent |
| Eye redness | May occur in sensitive individuals |
| Dry eye or blurred vision | Rare, short-term |
🧊 Storage:
-
Store at below 25°C
-
Protect from light and moisture
-
Use within 28 days after opening
🔄 Alternative Brands (India):
| Brand Name | Strength | Manufacturer |
|---|---|---|
| Lastacaft | Alcaftadine 0.25% | Allergan |
| Alcarex | Alcaftadine 0.25% | Ajanta Pharma |
| Alcain | Alcaftadine 0.25% | Cipla |






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