Description
Tretin-Iso 20 – Strip of 10 Capsules
Type: Prescription medicine
Form: Soft gelatin capsule
Pack: Strip of 10 capsules
✅ Composition (per capsule):
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Isotretinoin IP – 20 mg
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Excipients – q.s. (quantum satis – as required to make the full formulation)
💊 Uses:
Tretin-Iso 20 is used for treating moderate to severe acne, especially:
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Nodular acne
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Cystic acne
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Acne unresponsive to antibiotics or topical therapy
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Off-label: Hidradenitis suppurativa, rosacea (only under specialist care)
⚙️ Mechanism of Action:
Isotretinoin works by:
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Reducing sebum (oil) production
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Preventing clogged pores
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Decreasing inflammation
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Suppressing Propionibacterium acnes (acne-causing bacteria)
⚠️ Critical Safety Information:
🚫 Pregnancy Risk – Category X (Do Not Use in Pregnancy):
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Causes severe birth defects
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Women must use 2 forms of birth control during and 1 month after therapy
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Monthly pregnancy tests are mandatory
🧪 Monitoring While on Treatment:
| Test | Frequency |
|---|---|
| Liver Function Test (LFT) | Monthly or as advised |
| Lipid Profile | Monthly |
| Pregnancy Test (females) | Monthly |
| CBC (sometimes) | Periodically |
🔄 Common Side Effects:
| Symptom | Management Suggestion |
|---|---|
| Dry lips, skin | Use lip balm and moisturizers |
| Dry eyes | Use artificial tears |
| Nosebleeds | Apply petroleum jelly in nostrils |
| Joint/muscle aches | Light exercise, avoid overexertion |
| Sun sensitivity | Wear sunscreen (SPF 30+), avoid sun |
| Mood changes (rare) | Report to doctor immediately |
🧴 Usage Tips:
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Take with fatty food for better absorption
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Do not crush or chew the capsule
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Continue using gentle skincare products
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Avoid waxing, laser, or aggressive facial treatments
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