Description

Stator CV 20 – Strip of 15 Capsules

combination product containing Atorvastatin and Clopidogrel, which are used together to manage cholesterol levels and reduce the risk of cardiovascular events, such as heart attacks and strokes.

Composition:

• Atorvastatin Calcium I.P.: Each dose is equivalent to Atorvastatin 20 mg, provided by two film-coated Atorvastatin tablets (each containing 10 mg of Atorvastatin).
• Clopidogrel Bisulphate I.P.: Clopidogrel is an antiplatelet medication that helps prevent blood clots.

Purpose and Uses:

1. Atorvastatin (20 mg):
   • Statin medication used to lower cholesterol and reduce triglycerides in the blood.
   • It works by inhibiting the HMG-CoA reductase enzyme, which reduces the production of LDL cholesterol (“bad cholesterol”) in the liver.
   • Reduces the risk of cardiovascular events like heart attacks, strokes, and peripheral artery disease by improving the lipid profile.
2. Clopidogrel (Dosage unspecified but standard as 75 mg):
   • Antiplatelet agent that prevents blood clots by blocking a receptor on platelets, thus reducing the risk of clot formation.
   • Often prescribed for people who have had a heart attack, stroke, or those undergoing angioplasty or stent placement, as it helps prevent clotting that could lead to another cardiovascular event.

Combination Benefits:

This combination is particularly useful for individuals who are at risk of cardiovascular diseases or have already experienced heart-related issues. The combination of Atorvastatin and Clopidogrel works in two ways:

• Atorvastatin reduces cholesterol and plaque buildup in the arteries.
• Clopidogrel helps prevent blood clots, which can form at the site of atherosclerotic plaque and lead to blockages that could cause heart attacks or strokes.

Common Uses:

• Post-heart attack or stroke prevention: The combination helps prevent further heart attacks, strokes, or other thrombotic events.
• Angioplasty or stent placement: Reduces the risk of clot formation following procedures that open or insert a stent into blocked arteries.
• High cardiovascular risk: In patients with multiple risk factors for cardiovascular disease, this combination can offer significant protection.

Dosage:

The typical dosage would be based on your doctor’s recommendation, depending on your condition and cardiovascular risk factors. However, a general dosage might be:

• Atorvastatin: 20 mg, usually taken once daily (in the form of two 10 mg tablets).
• Clopidogrel: The standard dose is often 75 mg once daily, but this can vary based on the individual patient’s needs.

Side Effects:

1. Atorvastatin:
   • Muscle pain or weakness (myopathy, in rare cases, can lead to rhabdomyolysis).
   • Liver enzyme abnormalities, so liver function should be monitored.
   • Gastrointestinal issues (nausea, diarrhea, constipation).
   • Increased blood sugar: May increase the risk of developing diabetes in some patients.
2. Clopidogrel:
   • Bleeding complications: As an antiplatelet drug, it increases the risk of bleeding (including easy bruising, nosebleeds, or gastrointestinal bleeding).
   • Headache or dizziness.
   • Gastrointestinal issues like nausea or diarrhea.

Precautions:

• Liver or kidney disease: Both medications require caution in people with liver or kidney issues. Regular monitoring is required.
• Pregnancy and breastfeeding: Atorvastatin should not be used during pregnancy or breastfeeding as it may harm the fetus or infant.
• Bleeding disorders: Clopidogrel should be used with caution in individuals with a history of bleeding disorders, and patients should be closely monitored.
• Drug interactions: Both Atorvastatin and Clopidogrel can interact with other medications, such as anticoagulants, other cholesterol-lowering drugs, or certain antibiotics, so it’s important to inform your healthcare provider of any other medications you’re taking.