Description

Nexpro RD 40 – Strip of 10 Capsules

Nexpro RD 40 is a medication that contains Esomeprazole (40 mg) along with Domperidone (10 mg). This combination is designed to treat digestive issues where both acid reflux and motility problems (like delayed gastric emptying) are involved.

Composition:

• Esomeprazole 40 mg
• Domperidone 10 mg
• Form: Capsules (10 capsules per strip)

About the Components:

1. Esomeprazole (40 mg):
   Esomeprazole is a proton pump inhibitor (PPI) that works by reducing stomach acid production. It’s typically used for conditions like GERD, peptic ulcers, gastritis, and other acid-related disorders.
2. Domperidone (10 mg):
   Domperidone is a prokinetic agent, which means it helps improve the movement of the stomach and intestines. It promotes gastric emptying and helps reduce symptoms like nausea, vomiting, and bloating. Domperidone is often used to treat conditions related to delayed gastric emptying (gastroparesis) and nausea associated with various digestive disorders.

Common Uses of Nexpro RD 40:

This combination of Esomeprazole and Domperidone is prescribed for conditions that involve both acid reflux and impaired motility, such as:

• Gastroesophageal reflux disease (GERD): For both controlling acid production and improving gastric motility to reduce reflux.
• Gastroparesis: A condition in which the stomach doesn’t empty properly, leading to symptoms like nausea, vomiting, and bloating.
• Dyspepsia (indigestion): When there’s a combination of stomach discomfort, acid reflux, and slow gastric emptying.
• Nausea and vomiting: Domperidone helps control nausea associated with gastric acid problems.

How It Works:

• Esomeprazole reduces stomach acid production by blocking proton pumps in the stomach lining.
• Domperidone helps with gastric motility by enhancing the movement of the stomach and intestines, aiding in quicker gastric emptying and preventing acid reflux.

Dosage:

• The typical dose is 1 capsule (40 mg Esomeprazole and 10 mg Domperidone) per day, often taken before meals.
• The exact dosage and duration of treatment should be determined by a healthcare provider, depending on the condition being treated.

Possible Side Effects:

• Common side effects:
  • Headache
  • Nausea or dry mouth
  • Abdominal pain or discomfort
  • Diarrhea or constipation
• Serious side effects (rare but can include):
  • Cardiac arrhythmias (irregular heartbeats) due to Domperidone
  • Extrapyramidal symptoms (movement disorders), especially in the elderly
  • Low magnesium levels (with prolonged use of Esomeprazole)
  • Kidney or liver issues

Precautions:

• Kidney and liver function: If you have liver or kidney problems, consult your doctor before using Nexpro RD.
• Cardiac health: Domperidone has been associated with a risk of cardiac arrhythmias, particularly in people with heart disease, so this should be carefully considered by your healthcare provider.
• Long-term use: Prolonged use of Esomeprazole can lead to side effects like bone fractures, magnesium deficiency, or vitamin B12 deficiency.

Warnings:

• Pregnancy and breastfeeding: It’s essential to consult a healthcare provider before using Nexpro RD 40 during pregnancy or breastfeeding.
• Drug interactions: Inform your doctor about any other medications you are taking, as Domperidone and Esomeprazole may interact with certain drugs, including other medications that affect heart rhythm, blood thinners, and some antifungals.