Description
Isotroin-20 Softgel – Strip of 15 Capsules is a prescription medicine used to treat severe acne (such as nodular or cystic acne) that has not responded to conventional therapies, including oral antibiotics and topical treatments.
✅ Composition:
Each soft gelatin capsule contains:
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Isotretinoin IP 20 mg
(A synthetic retinoid derived from Vitamin A)
💊 Therapeutic Uses:
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Severe nodulocystic acne
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Acne unresponsive to antibiotics
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Sometimes used off-label for:
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Rosacea
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Folliculitis
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Hidradenitis suppurativa
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🔄 How It Works:
Isotretinoin reduces the size and activity of sebaceous (oil) glands and decreases inflammation, helping to clear the skin over time. It also prevents new acne formation by reducing bacterial growth and clogged pores.
🕒 Dosage Guidelines:
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Taken once or twice daily with fatty food (for better absorption).
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The course usually lasts 16–20 weeks, but can vary.
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Dosage is often weight-based, and adjusted during treatment by a dermatologist.
⚠️ Strict Warnings & Precautions:
🚫 Pregnancy Category X (Highest risk):
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Absolutely contraindicated in pregnancy due to severe birth defects.
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Mandatory to use 2 forms of contraception:
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1 month before, during, and 1 month after therapy.
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Regular pregnancy tests required for women of childbearing age.
🧪 Regular Monitoring Required:
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Liver function tests
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Lipid profile
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CBC (blood count)
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Pregnancy test (females)
🔄 Common Side Effects:
Side Effect | Description |
---|---|
Dry lips & skin | Most common; use lip balm and moisturizers |
Dry eyes / Irritation | Use artificial tears |
Joint/muscle pain | Occasional |
Photosensitivity | Use sunscreen (SPF 30+) |
Mood changes (rare) | Monitor and inform doctor if noticed |
❗ Do Not:
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Donate blood during and 1 month after stopping
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Take Vitamin A supplements
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Undergo waxing or cosmetic skin procedures during and shortly after treatment
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