Description

Defza 30 – Strip of 6 Tablets

Defza 30mg is a tablet formulation containing Deflazacort, a corticosteroid medication that is used to treat various inflammatory and autoimmune conditions due to its anti-inflammatory and immunosuppressive effects.

Composition:

Each tablet of Defza 30mg contains 30 mg of Deflazacort as the active ingredient.

Indications:

Deflazacort is commonly prescribed for conditions that involve inflammation or immune system dysfunction. Some of the common uses of Defza 30mg include:

• Autoimmune diseases: Such as rheumatoid arthritis, systemic lupus erythematosus, and other inflammatory disorders.
• Inflammatory conditions: Such as inflammatory bowel disease (IBD), dermatitis, or vasculitis.
• Severe allergic reactions: For example, in acute asthma exacerbations or anaphylaxis.
• Muscle wasting diseases: Such as Duchenne muscular dystrophy.
• Organ inflammation: For conditions like nephrotic syndrome (kidney inflammation) or other inflammatory conditions affecting organs.

Mechanism of Action:

Deflazacort works by:

• Reducing inflammation: It inhibits the production of inflammatory chemicals (like prostaglandins) that cause inflammation.
• Suppressing the immune system: It reduces the immune response, which is useful in autoimmune diseases where the immune system mistakenly attacks the body’s own tissues.

Dosage:

The dosage of Defza 30mg will depend on the condition being treated, the severity of the condition, and the patient’s weight. The usual dosage is as follows:

• Adults: The typical starting dose is between 0.1 to 0.3 mg per kg body weight per day.
• Children: The dose will depend on the child’s weight and the condition being treated.

Defza 30mg is usually taken once a day, in the morning to reduce the risk of insomnia. It should be taken with food to minimize gastrointestinal side effects.

Side Effects:

Like all corticosteroids, Defza 30mg can cause a variety of side effects, especially with long-term use. Common side effects may include:

• Weight gain (due to fluid retention and increased appetite)
• Increased blood pressure
• Elevated blood sugar levels (hyperglycemia), which may worsen diabetes
• Gastrointestinal discomfort (e.g., ulcers, indigestion)
• Osteoporosis (bone thinning with long-term use)
• Mood changes (e.g., irritability, anxiety, or depression)
• Increased risk of infections due to immune system suppression
• Cataracts or glaucoma (eye issues, particularly with prolonged use)

Precautions:

• Tapering: If you have been on Defza 30mg for an extended period, it is important not to stop the medication suddenly. Tapering the dose gradually, under a healthcare provider’s supervision, is necessary to avoid withdrawal symptoms and adrenal insufficiency.
• Infection Risk: Since corticosteroids suppress the immune system, you may be more prone to infections. Any symptoms of infection should be reported to your healthcare provider.
• Bone Health: Prolonged use of corticosteroids like Defza 30mg can lead to bone thinning (osteoporosis). Calcium and vitamin D supplements may be recommended, and bone density should be monitored.
• Diabetes: Regular monitoring of blood glucose levels is important for patients with diabetes, as corticosteroids can raise blood sugar levels.
• Pregnancy and Breastfeeding: Defza 30mg should be used during pregnancy only if the benefits outweigh the risks. It is also excreted in breast milk, so breastfeeding mothers should consult their healthcare provider before using this medication.

Administration:

• Defza 30mg tablets should be taken as prescribed, usually once a day, preferably in the morning.
• The tablet should be taken with food to reduce the risk of gastrointestinal side effects.
• Swallow the tablet whole without crushing or chewing it.