Defcort TM – Tablets 10’s

Description

Defcort TM is a combination medication that contains two active ingredients: Deflazacort (a corticosteroid) and Tamsulosin Hydrochloride (an alpha-blocker). The combination of these two drugs is used to treat conditions related to both inflammation and prostate issues.

Composition:

Each tablet of Defcort TM contains:

• Deflazacort 30 mg (Corticosteroid)
• Tamsulosin Hydrochloride 0.4 mg (Alpha-1 receptor antagonist)

Indications:

The combination of Deflazacort and Tamsulosin in Defcort TM is used for conditions that involve both inflammation and prostate issues. Specifically, it may be prescribed for:

1. Inflammatory conditions: Deflazacort helps manage inflammation associated with conditions like rheumatoid arthritis, systemic lupus erythematosus, or other autoimmune disorders.
2. Benign Prostatic Hyperplasia (BPH): Tamsulosin is used to treat symptoms of BPH, such as difficulty urinating, by relaxing the muscles of the prostate and bladder neck.

Mechanism of Action:

• Deflazacort (Corticosteroid): It reduces inflammation by inhibiting the production of inflammatory chemicals like prostaglandins and suppresses immune system activity.
• Tamsulosin (Alpha-1 Blocker): It works by relaxing the smooth muscles in the prostate and the bladder neck, making it easier to urinate. This helps alleviate symptoms of BPH.

Dosage:

• The dosage of Defcort TM is typically one tablet per day, but the exact dosage should be determined by your healthcare provider based on the specific condition being treated.
• Deflazacort 30 mg is the standard dose for many inflammatory conditions, while Tamsulosin 0.4 mg is a standard dose for BPH management.

Side Effects:

Like all medications, Defcort TM may cause side effects, although not everyone experiences them. Some common side effects include:

• Deflazacort-related side effects:
  • Weight gain (due to fluid retention and increased appetite)
  • Elevated blood pressure
  • Gastrointestinal irritation, such as indigestion or ulcers
  • Increased blood sugar levels (which may worsen diabetes)
  • Osteoporosis (bone thinning with long-term use)
  • Mood changes, such as anxiety or irritability
• Tamsulosin-related side effects:
  • Dizziness or lightheadedness (especially when standing up quickly)
  • Headache
  • Nasal congestion
  • Ejaculation disorders (e.g., retrograde ejaculation)
  • Fatigue

Precautions:

• Deflazacort-related precautions:
  • Tapering: Long-term corticosteroid therapy should not be stopped abruptly; the dose should be gradually reduced to prevent withdrawal symptoms and adrenal insufficiency.
  • Infections: Corticosteroids can suppress the immune system, making you more susceptible to infections.
  • Bone health: Long-term use of corticosteroids can lead to osteoporosis, so bone density monitoring may be necessary.
• Tamsulosin-related precautions:
  • Hypotension: Tamsulosin can cause a sudden drop in blood pressure, especially when standing, which may result in dizziness or fainting. It’s important to stand up slowly from sitting or lying down.
  • Kidney or liver issues: If you have kidney or liver problems, the dose may need to be adjusted.

Administration:

• • Defcort TM should be taken as prescribed by your healthcare provider, usually once a day.
  • It should be taken with food to reduce the risk of gastrointestinal side effects.
  • Swallow the tablet whole and do not crush or chew it.