Defcort – 30ml Suspension

Description

Defcort Suspension is a liquid formulation of Deflazacort, a corticosteroid medication used primarily for its anti-inflammatory and immunosuppressive properties. This form is often used when a patient cannot take tablets or prefers a liquid form for easier administration, especially in children.

Composition:

Each 5 ml of the Defcort Suspension typically contains 6 mg of Deflazacort (similar to the tablet form of Defcort 6).

Indications:

Deflazacort suspension is prescribed for a range of conditions, including:

• Autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus)
• Inflammatory conditions (e.g., inflammatory bowel disease, dermatitis)
• Allergic conditions (e.g., severe allergies, asthma)
• Muscle wasting diseases (e.g., Duchenne muscular dystrophy)
• Acute flare-ups of certain chronic conditions

Dosage:

• The dosage of Defcort Suspension depends on the condition being treated and the patient’s age, weight, and response to treatment. It’s often administered in divided doses.
• The general dosing guideline for adults is around 0.1 mg to 0.3 mg per kg of body weight per day, but it can vary. The dose for children is usually based on their weight and the condition being treated.
• The suspension should be shaken well before use to ensure the correct dose is taken.
• The typical dose for children may start at 1–2 mg per kg of body weight per day, depending on the condition.

Mechanism of Action:

Deflazacort is a corticosteroid, which works by reducing inflammation and modifying the immune system’s response. It does so by inhibiting the production of certain chemicals that cause inflammation (prostaglandins) and suppressing the immune system, which can be beneficial in autoimmune conditions.

Side Effects:

Corticosteroids like Deflazacort can cause a range of side effects, especially with prolonged use. Some potential side effects include:

• Weight gain due to fluid retention and increased appetite
• Increased blood sugar levels (hyperglycemia), which may be a concern for diabetic patients
• High blood pressure
• Gastrointestinal issues, such as stomach ulcers or indigestion
• Suppressed immune system, which increases the risk of infections
• Mood changes, such as irritability, anxiety, or depression
• Osteoporosis (bone thinning) with long-term use
• Cataracts or glaucoma (eye issues)

Precautions:

• Tapering: When stopping corticosteroids like Deflazacort, it’s important to gradually reduce the dose rather than stopping abruptly, to avoid withdrawal symptoms and adrenal insufficiency.
• Gastrointestinal risks: If you have a history of ulcers or gastrointestinal bleeding, you should take this medication with caution.
• Infections: Since corticosteroids suppress the immune system, you should avoid contact with people who have contagious diseases and monitor for signs of infection.
• Diabetes: Regular monitoring of blood sugar levels is important, as corticosteroids can increase glucose levels.
• Pregnancy and breastfeeding: Corticosteroids should be used during pregnancy only if clearly needed, and it is excreted in breast milk, so breastfeeding mothers should consult a healthcare provider before use.

Administration:

• Shake the bottle well before using to ensure the correct dosage.
• The liquid can be administered using the provided measuring device (e.g., a measuring spoon or dropper).
• It should be taken with food or milk to reduce the risk of gastrointestinal irritation.

Conclusion:

Defcort Suspension (Deflazacort) is an effective treatment for a variety of inflammatory and autoimmune conditions. Like all corticosteroids, it must be used under medical supervision to manage potential side effects and ensure proper dosing. The liquid form makes it easier to administer, especially for children or individuals who have difficulty swallowing tablets.

If you have any questions about the medication, dosage, or side effects, feel free to ask!