Description
Defcort 12mg – Tablets 6’s
Defcort 12mg is a tablet formulation containing Deflazacort, a corticosteroid used for its anti-inflammatory and immunosuppressive properties.
Composition:
Each tablet of Defcort 12mg contains 12 mg of Deflazacort as the active ingredient.
Indications:
Deflazacort is commonly used for treating various conditions, including:
- Autoimmune diseases: Such as rheumatoid arthritis, lupus, and other inflammatory disorders.
- Inflammatory conditions: Such as inflammatory bowel disease, dermatitis, or vasculitis.
- Allergic reactions: Severe allergies, including asthma exacerbations.
- Muscle wasting diseases: For example, Duchenne muscular dystrophy.
- Organ inflammation: Conditions like nephrotic syndrome (kidney inflammation) or other inflammatory diseases affecting organs.
Mechanism of Action:
Deflazacort, like other corticosteroids, works by:
- Reducing inflammation: It inhibits the release of pro-inflammatory substances such as prostaglandins.
- Suppressing the immune system: It suppresses immune activity, which is beneficial in treating autoimmune diseases where the immune system attacks healthy cells.
Dosage:
- The dosage of Defcort 12mg will depend on the condition being treated, the severity of the condition, and the patient’s weight.
- The typical starting dose for adults can range from 0.1 to 0.3 mg per kg of body weight per day.
- For children, the dose is often based on their weight and the specific condition.
- Defcort 12mg is typically taken once daily, usually in the morning to reduce the risk of insomnia. It should be taken with food to minimize gastrointestinal irritation.
Side Effects:
As with other corticosteroids, Defcort 12mg can cause a range of side effects, especially with long-term use. Some common side effects include:
- Weight gain (due to fluid retention and increased appetite)
- Elevated blood pressure
- Increased blood sugar levels (hyperglycemia), which can worsen diabetes
- Gastrointestinal discomfort (e.g., stomach ulcers, indigestion)
- Osteoporosis (bone thinning with prolonged use)
- Mood changes (e.g., irritability, anxiety, depression)
- Increased risk of infections due to immune system suppression
- Cataracts or glaucoma (eye issues, particularly with long-term use)
Precautions:
- Tapering: If you have been on Defcort 12mg for a long period, the medication should not be stopped abruptly. A gradual reduction (tapering) of the dose is necessary to avoid withdrawal symptoms and adrenal insufficiency.
- Infection risk: Corticosteroids can suppress the immune system, making you more vulnerable to infections. It is important to avoid exposure to contagious diseases and report any signs of infection immediately.
- Bone health: Long-term use of corticosteroids can lead to bone thinning, so calcium and vitamin D supplements may be recommended, along with monitoring bone density.
- Diabetes: Regular blood sugar monitoring is necessary, as corticosteroids can increase blood glucose levels.
- Pregnancy and breastfeeding: Deflazacort should be used during pregnancy only if clearly needed. It is excreted in breast milk, so breastfeeding mothers should consult their doctor before using this medication.
Administration:
- Defcort 12mg tablets should be taken once a day, typically in the morning.
- The tablets should be taken with food to minimize stomach irritation.
- Swallow the tablet whole; do not chew or crush it.
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