Description

CTD-T 6.25/80 Strip of 15 Tablets

Overview

CTD-T 6.25/80 is a fixed-dose combination antihypertensive medication containing Chlorthalidone 6.25 mg and Telmisartan 80 mg. It is designed for the treatment of high blood pressure (hypertension) in patients who require stronger control, especially when monotherapy is insufficient. By combining a diuretic and an angiotensin receptor blocker (ARB), this medicine provides enhanced, long-lasting, and stable blood pressure reduction.

---

Composition

Each uncoated tablet contains:

• Chlorthalidone IP – 6.25 mg

• Telmisartan IP – 80 mg

---

Description

CTD-T 6.25/80 offers a dual mechanism for more effective BP control:

1. Chlorthalidone (6.25 mg)

A thiazide-like diuretic that:

• Increases urine output

• Eliminates excess sodium and water

• Reduces circulating blood volume

• Lowers pressure in the blood vessels

Even at the low dose of 6.25 mg, Chlorthalidone provides smooth, sustained BP reduction for up to 48–72 hours.

2. Telmisartan (80 mg)

A long-acting ARB (Angiotensin II Receptor Blocker) that:

• Relaxes and widens blood vessels

• Blocks the hormone that causes vessel tightening

• Provides full 24-hour coverage

• Reduces the workload on the heart

Telmisartan 80 mg is considered a high-strength dose, ideal for patients who require robust BP control.

Together, these medicines deliver enhanced antihypertensive action by reducing fluid overload and improving vascular relaxation.

---

Uses

CTD-T 6.25/80 is prescribed for:

• Primary hypertension (high blood pressure)

• Patients not controlled with Telmisartan alone

• Moderate to severe hypertension

• Preventing cardiovascular complications, including:

  • Stroke

  • Heart attack

  • Heart failure

  • Hypertensive kidney damage

It is especially helpful in:

• Patients with high cardiovascular risk

• Long-standing hypertension

• Salt-sensitive patients

• Diabetic or kidney-related high BP

---

How CTD-T 6.25/80 Works

Chlorthalidone

• Inhibits sodium chloride reabsorption in kidneys

• Increases excretion of water and electrolytes

• Reduces blood volume

• Lowers peripheral vascular resistance

Telmisartan

• Blocks angiotensin II receptors

• Dilates arteries and veins

• Controls BP throughout 24 hours

• Protects heart and kidneys

Together, they provide powerful and sustained BP control.

---

Benefits

• Dual-action therapy ensures stronger BP reduction

• Long-acting (once-daily dosing)

• Reduces risk of stroke and heart attack

• Suitable for patients needing high-dose ARB therapy

• Less chance of cough compared to ACE inhibitors

• Effective even in resistant hypertension

---

Side Effects

Most side effects are mild and manageable.

Common Side Effects

• Increased urination

• Dizziness or lightheadedness

• Fatigue

• Headache

• Dry mouth

Less Common Side Effects

• Low potassium levels

• Low sodium levels

• Slight increase in creatinine

• Muscle cramps

• Increased uric acid (possible gout flare)

• Low blood pressure (hypotension), especially initially

---

Precautions

• Check BP regularly

• Monitor kidney function & electrolytes

• Avoid potassium supplements unless prescribed

• Use with caution in kidney or liver disease

• Not recommended during pregnancy

• Avoid dehydration and excessive alcohol

---

Drug Interactions

CTD-T 6.25/80 may interact with:

• NSAIDs

• Lithium

• Other antihypertensives

• Diuretics

• Potassium supplements or salt substitutes

• Antidiabetic medications

---

Storage

• Store below 25°C

• Keep away from sunlight and moisture

• Store in the original blister pack

• Keep out of reach of children