Description

CTD-T 6.25/40 Strip of 15 Tablets

Overview

CTD-T 6.25/40 is a combination antihypertensive medication containing Chlorthalidone 6.25 mg and Telmisartan 40 mg. This dual-action formulation is prescribed for the effective management of high blood pressure (hypertension), especially in patients who require more than one medication to achieve optimal blood pressure control. Combining a diuretic with an angiotensin receptor blocker (ARB) offers enhanced, long-lasting, and stable BP reduction.

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Composition

Each uncoated tablet contains:

• Chlorthalidone IP – 6.25 mg

• Telmisartan IP – 40 mg

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Description

CTD-T 6.25/40 works through two complementary mechanisms:

1. Chlorthalidone (6.25 mg)

A thiazide-like diuretic that helps lower blood pressure by:

• Increasing urine output

• Removing excess salt and water

• Reducing blood volume

• Lowering pressure on the blood vessels

Even at the low dose of 6.25 mg, Chlorthalidone provides prolonged BP-lowering action for up to 48–72 hours.

2. Telmisartan (40 mg)

An angiotensin II receptor blocker (ARB) that:

• Relaxes blood vessels

• Prevents narrowing of arteries

• Reduces strain on the heart

• Provides 24-hour sustained BP control

Together, these two medicines create a potent antihypertensive effect, offering better results than either drug alone.

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Uses

CTD-T 6.25/40 is prescribed for:

• Primary hypertension (high blood pressure)

• Patients not controlled on monotherapy

• Prevention of stroke, heart attack, and kidney damage

• Long-term BP maintenance

It is especially useful in patients with:

• High cardiovascular risk

• Chronic kidney disease (CKD)

• Diabetes-related hypertension

• Fluid retention associated with hypertension

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How CTD-T 6.25/40 Works

The combination works through:

Chlorthalidone:

• Removes excess sodium and water

• Reduces blood volume

• Lowers peripheral vascular resistance

Telmisartan:

• Blocks angiotensin II

• Dilates blood vessels

• Reduces blood pressure

• Protects heart and kidneys

This combination results in smooth, sustained, and effective BP control throughout the day.

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Benefits

• Dual mechanism ensures strong BP reduction

• Long-acting formulation with stable 24-hour control

• Helps reduce risk of heart-related complications

• Suitable for long-term hypertension management

• Works well even in salt-sensitive and elderly patients

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Side Effects

Most side effects are mild and temporary.

Common Side Effects:

• Increased urination

• Dizziness or lightheadedness

• Fatigue

• Headache

• Dry mouth

Less Common Side Effects:

• Low potassium levels

• Low sodium

• Increased uric acid (possible gout flare)

• Muscle cramps

• Slight increase in creatinine

• Hypotension (low BP) in sensitive patients

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Precautions

• Monitor BP regularly

• Check electrolytes, especially potassium & sodium

• Avoid potassium supplements unless prescribed

• Use caution in kidney or liver disease

• Avoid dehydration

• Not recommended during pregnancy

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Drug Interactions

CTD-T 6.25/40 may interact with:

• NSAIDs (reduce effect of the medicine)

• Lithium (risk of toxicity)

• Other diuretics

• ACE inhibitors / ARBs

• Antidiabetic medicines

• Potassium supplements or salt substitutes

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Storage

• Store below 25°C

• Protect from moisture and sunlight

• Keep in original blister pack

• Keep away from children