Description

CTD-6.25- Strip of 15 Tablets

 Complete Detailed Information

Overview

CTD-6.25 is a prescription diuretic medication containing Chlorthalidone 6.25 mg, used primarily to treat hypertension (high blood pressure) and edema (fluid retention). Chlorthalidone belongs to the class of thiazide-like diuretics, known for their long-acting and effective blood-pressure–lowering properties. Even at a small dose of 6.25 mg, it provides steady and sustained antihypertensive action for up to 24–72 hours.

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Composition

Each uncoated tablet contains:

• Chlorthalidone IP – 6.25 mg

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Detailed Description

CTD-6.25 is formulated as a low-dose diuretic to ensure effective blood pressure control while minimizing electrolyte disturbances such as low potassium or sodium levels. Chlorthalidone works by acting on the distal convoluted tubules of the kidneys, preventing the reabsorption of sodium and chloride. This increases urine output and reduces fluid volume in the bloodstream, leading to a significant reduction in blood pressure.

Because of its long half-life, CTD-6.25 provides stable BP control throughout the day, making it suitable for long-term hypertension management. It is often recommended as part of combination therapy along with ACE inhibitors, ARBs, beta-blockers, or calcium channel blockers.

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Uses

CTD-6.25 is prescribed for:

✔ Hypertension (High Blood Pressure)

Helps lower and maintain healthy blood pressure levels, reducing strain on the heart.

✔ Edema

Used in fluid retention conditions such as:

• Congestive heart failure

• Liver cirrhosis

• Kidney disorders (nephrotic syndrome, chronic kidney disease)

✔ Prevention of Hypertension-Related Complications

Long-term use helps reduce the risk of:

• Stroke

• Heart attack

• Kidney failure

• Hypertensive heart disease

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How CTD-6.25 Works (Pharmacology)

Chlorthalidone acts by:

• Inhibiting sodium and chloride reabsorption

• Increasing urine volume

• Decreasing circulating blood volume

• Reducing peripheral vascular resistance

These actions combined help in lowering blood pressure, reducing swelling, and improving cardiac workload.

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Advantages of CTD-6.25

• Long-acting diuretic with effects lasting over 24 hours

• Effective even at low doses

• Improves outcomes in hypertensive patients

• Reduces the workload on heart and kidneys

• Often used as first-line therapy in hypertension

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Side Effects

Most are mild and dose-dependent:

Common Side Effects

• Increased urination

• Dizziness or lightheadedness

• Weakness or fatigue

• Dry mouth

• Mild headache

Less Common

• Low potassium (hypokalemia)

• Low sodium (hyponatremia)

• Increased blood sugar

• Muscle cramps

• Gout flare (rare but possible)

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Precautions

• Avoid excessive salt intake, as it reduces effectiveness

• Patients with kidney or liver issues should use with caution

• Monitor electrolytes regularly

• Not recommended during pregnancy unless advised

• Patients with gout, diabetes, or dehydration should inform their doctor

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Drug Interactions

CTD-6.25 may interact with:

• ACE inhibitors / ARBs (may increase potassium imbalance)

• NSAIDs (may reduce effect of CTD-6.25)

• Lithium (raises lithium toxicity risk)

• Other diuretics

• Antidiabetic medications (may alter glucose levels)

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Storage

• Store below 25°C

• Keep away from direct sunlight and moisture

• Store in original packaging

• Keep out of reach of children