Description
Cetzine Tablet
Category: Antihistamine / Anti-allergic
Brand Name: Cetzine
Manufacturer: GlaxoSmithKline (GSK)
Pack Size: Strip of 15 film-coated tablets
Form: Oral tablet
Prescription: OTC (Over-the-counter in many regions, but doctor’s advice is preferred)
🔬 Composition (Per Tablet):
| Ingredient | Strength | Function |
|---|---|---|
| Cetirizine Hydrochloride IP | 10 mg | Second-generation H1 antihistamine – relieves allergy symptoms |
⚙️ Mechanism of Action:
-
Cetirizine selectively blocks histamine H1 receptors.
-
Histamine is responsible for allergic reactions like sneezing, itching, and nasal congestion.
-
Being a second-generation antihistamine, cetirizine causes minimal drowsiness compared to older agents like chlorpheniramine.
🩺 Indications / Uses:
Cetzine is used for:
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Allergic rhinitis (seasonal & perennial)
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Sneezing and runny nose
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Watery and itchy eyes
-
Skin allergies such as urticaria (hives) and dermatitis
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Dust/pollen/allergen-induced allergies
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Chronic idiopathic urticaria
📏 Dosage Guidelines:
| Age Group | Recommended Dose |
|---|---|
| Adults & Children ≥12 yrs | 1 tablet (10 mg) once daily |
| Children 6–12 yrs | 5 mg once or twice daily (or 10 mg once) |
| Children <6 yrs | Prefer Cetirizine syrup – dose based on weight |
| Elderly / Renal Impairment | Start with 5 mg daily under supervision |
Best taken at night, especially if mild drowsiness occurs.
⚠️ Precautions:
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May cause mild drowsiness or dizziness
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Avoid alcohol or sedatives during use
-
Use with caution in kidney or liver impairment
-
Safe in pregnancy (Category B) – but take only under doctor’s advice
-
Minimal drug interactions – generally safe
❌ Contraindications:
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Hypersensitivity to cetirizine or hydroxyzine derivatives
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Severe renal impairment (without dose adjustment)
⚠️ Side Effects:
| Common (mild) | Rare/Serious |
|---|---|
| Drowsiness (rare) | Allergic reaction (rash, swelling) |
| Dry mouth | Palpitations (very rare) |
| Headache, fatigue | Liver enzyme changes (rare) |
🔁 Alternative Brands (Same Molecule – Cetirizine 10 mg):
| Brand Name | Manufacturer |
|---|---|
| Alerid | Cipla |
| Zyrtec | Dr. Reddy’s |
| Okacet | GlaxoSmithKline (alternate) |
| Cetcip | Cipla |
| Cetrizet | Sun Pharma |
| Cetzine-L | Contains Levocetirizine (active form of cetirizine) |
📦 Storage:
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Store below 25°C
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Keep away from moisture and direct sunlight
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Keep out of reach of children
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