Description
Astymin-3 Injection
1. Composition (Per ml)
Astymin-3 contains a balanced profile of essential amino acids along with sorbitol, designed to support nutritional recovery:
| Ingredient | Strength | Role |
|---|---|---|
| L-Arginine HCl USP | 8.0 mg | Improves blood flow, promotes wound healing, supports immunity |
| L-Histidine HCl H₂O BP | 4.0 mg | Helps tissue repair, hemoglobin production |
| L-Isoleucine USP | 5.5 mg | Muscle repair, energy regulation |
| L-Leucine USP | 12.3 mg | Stimulates muscle protein synthesis |
| L-Lysine HCl USP | 22.3 mg | Collagen formation, calcium absorption, tissue recovery |
| L-Methionine USP | 7.1 mg | Liver detoxification, antioxidant activity |
| L-Phenylalanine USP | 8.7 mg | Neurotransmitter precursor, improves mood & recovery |
| L-Threonine USP | 5.4 mg | Immune support, collagen production |
| L-Tryptophan USP | 1.8 mg | Precursor for serotonin & melatonin |
| L-Valine USP | 6.1 mg | Muscle regeneration, stress recovery |
| Glycine IP | 10 mg | Enhances digestion, supports metabolism |
| Sorbitol IP | 50 mg | Provides energy source, stabilizer |
| Water for Injection IP | q.s. | Solvent |
2. Overview
Astymin-3 is a sterile IV amino acid infusion used in hospitals to support:
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Nutritional deficiencies
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Post-operative recovery
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General weakness
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Debility after acute or chronic illness
It enhances protein synthesis, improves nitrogen balance, and accelerates healing.
3. Pharmacological Action
Astymin-3 contains essential amino acids, which cannot be synthesized by the body and must be supplied externally.
Key pharmacological effects:
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Promotes protein synthesis: Essential for tissue repair and growth
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Maintains nitrogen balance: Supports healing after surgeries & infections
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Improves metabolism: Enhances overall recovery
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Boosts immunity: Needed for antibody production
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Assists liver detoxification: Due to methionine and lysine
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Supports neuromuscular function: Through BCAA (valine, leucine, isoleucine)
4. Indications (Uses)
Astymin-3 is used under medical supervision for:
A. Nutritional Support
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Severe malnutrition
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Protein deficiency
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Poor oral intake
B. Post-operative recovery
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Major surgeries
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Burns
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Trauma
C. Critical care
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ICU patients
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Prolonged hospitalization
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Chronic illness requiring nutritional supplementation
D. Other conditions
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Weakness and fatigue
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Liver disorders
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Debility in elderly
5. Dosage (General Guidance – As per doctor only)
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Administered intravenously (IV)
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Should be given slowly by infusion
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Dose depends on patient weight, condition, and nutritional requirement
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Never inject undiluted directly into vein
6. Contraindications
Astymin-3 should not be used in:
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Severe liver failure
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Severe kidney impairment
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Patients with amino acid metabolism disorders
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Known hypersensitivity to any ingredient
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In shock or severe dehydration unless stabilized
7. Precautions
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Must be administered by trained medical professionals
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Monitor electrolytes, renal function, and liver function
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Inject slowly to avoid vein irritation
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Caution in patients with:
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Heart failure
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Severe infection
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Edema or fluid overload
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8. Possible Side Effects
Astymin-3 is generally safe but may cause:
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Local burning or pain at injection site
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Nausea or vomiting
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Mild fever
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Allergic reaction (rare)
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Vein irritation if given too fast
9. Storage Instructions
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Store protected from light
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Temperature not exceeding 30°C
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Do not freeze
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Keep ampoule in carton until use
10. Manufacturer / Marketer
Tablets (India) Limited




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