Description
Acenac-MR is a combination medication that contains Thiocolchicoside, Aceclofenac, and Paracetamol. It is used primarily for pain relief and inflammation control, especially in conditions related to musculoskeletal pain and muscle spasms.
Composition:
- Thiocolchicoside 4 mg
- Aceclofenac 100 mg
- Paracetamol (Acetaminophen) 325 mg
How Each Component Works:
- Thiocolchicoside (4 mg):
- Muscle Relaxant: Thiocolchicoside is a muscle relaxant that helps reduce muscle spasms and stiffness. It works by acting on the central nervous system to relieve spasm-related pain, making it particularly useful in conditions like muscle strain, sprains, and other musculoskeletal disorders.
- Aceclofenac (100 mg):
- NSAID (Nonsteroidal Anti-Inflammatory Drug): Aceclofenac reduces pain and inflammation by inhibiting the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. It is used to treat conditions like arthritis, back pain, and muscle pain.
- Paracetamol (325 mg):
- Analgesic and Antipyretic: Paracetamol is a pain reliever and fever reducer. It helps manage mild to moderate pain, such as headache, muscle pain, or fever. It works through a different mechanism than NSAIDs, targeting the brain’s pain centers.
Indications:
Acenac-MR is used for the treatment of:
- Musculoskeletal pain (e.g., muscle strain, sprains)
- Pain associated with inflammation (e.g., arthritis, back pain)
- Muscle spasms: Due to its muscle relaxant properties, it helps relieve pain from muscle cramps and spasms.
Dosage:
- The typical dosage is 1 tablet twice a day (morning and evening), but it should always be used as prescribed by your physician.
- The dosage may vary depending on the severity of the condition and the individual patient’s health profile.
Common Side Effects:
While Acenac-MR is effective for pain relief and inflammation, it may cause some side effects, including:
- Gastrointestinal issues: Nausea, upset stomach, or indigestion (common with NSAIDs like Aceclofenac).
- Drowsiness or dizziness: Due to the muscle relaxant effects of Thiocolchicoside.
- Headache: Often a side effect of Paracetamol or Aceclofenac.
- Rashes or allergic reactions.
- In rare cases: More serious side effects like gastrointestinal bleeding, liver, or kidney issues (especially with prolonged use).
Warnings and Precautions:
- Gastrointestinal Risk: Like other NSAIDs, Aceclofenac can cause stomach ulcers or bleeding, especially if used for extended periods. It is advised to take it with food or milk to reduce stomach irritation.
- Kidney and Liver Function: Use with caution if you have kidney or liver problems, as NSAIDs and Paracetamol can strain these organs.
- Pregnancy and Breastfeeding: Thiocolchicoside and Aceclofenac are generally not recommended during pregnancy, especially in the third trimester. Consult your doctor if you are pregnant or breastfeeding.
- Allergies: If you have known allergies to any of the components (such as paracetamol, aceclofenac, or thiocolchicoside), you should avoid using this medication.
Storage:
- Store in a cool, dry place away from direct light and moisture.
- Keep out of reach of children.
Summary:
Acenac-MR combines three effective ingredients:
- Thiocolchicoside to relax muscles and reduce spasms.
- Aceclofenac to relieve pain and reduce inflammation.
- Paracetamol to provide pain relief and reduce fever.
This combination is useful for treating pain and inflammation associated with musculoskeletal conditions and muscle spasms. Always follow the prescribed dosage and consult your healthcare provider for guidance, especially if you have underlying medical conditions or are on other medications.
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Aceclo is a medication containing Aceclofenac as its active ingredient. It is commonly prescribed for its anti-inflammatory, analgesic (pain-relieving), and antipyretic (fever-reducing) effects.
Composition:
- Aceclofenac 100 mg per film-coated tablet.
- Excipients: These are inactive substances used in the formulation of the tablet (e.g., binders, fillers, coating agents) to help in the manufacturing and stability of the medication. The exact excipients are generally not listed in the basic composition but may include substances like starch, lactose, and magnesium stearate.
What is Aceclofenac?
- Aceclofenac is a Nonsteroidal Anti-Inflammatory Drug (NSAID). It works by inhibiting the activity of cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the production of prostaglandins—chemicals in the body that cause inflammation, pain, and fever.
- Aceclofenac is considered to be a selective COX-2 inhibitor, which means it mainly targets the inflammation-causing prostaglandins without affecting COX-1 (which protects the stomach lining). This makes it somewhat gentler on the stomach compared to some other NSAIDs.
Indications:
Aceclofenac is used to treat:
- Arthritis: Both osteoarthritis and rheumatoid arthritis.
- Pain: For conditions such as musculoskeletal pain, back pain, dental pain, and post-operative pain.
- Inflammation: For inflammatory conditions like tendonitis, bursitis, and gout.
- Fever: Although Aceclofenac is mainly used for pain and inflammation, it can also be used to reduce fever.
Dosage:
- The usual dose is 1 tablet (100 mg) once or twice a day, depending on the severity of the condition and the advice of the healthcare provider.
- Always follow the prescribed dosage instructions as provided by your doctor. Typically, taking the medication with food or milk can help minimize potential stomach irritation.
Side Effects:
As with most NSAIDs, Aceclofenac can cause side effects, including:
- Gastrointestinal issues: Nausea, dyspepsia (indigestion), or stomach pain. Rarely, ulcers, bleeding, or perforation of the gastrointestinal tract can occur with long-term use.
- Headaches or dizziness.
- Rashes or allergic reactions (though these are less common).
- Elevated liver enzymes (rarely), especially with prolonged use.
- Kidney issues: Prolonged use of Aceclofenac can, in rare cases, affect kidney function.
Warnings and Precautions:
- Gastrointestinal Risk: NSAIDs like Aceclofenac can increase the risk of gastrointestinal bleeding, ulceration, or perforation, especially in people with a history of stomach ulcers or digestive disorders. Taking the medicine with food can help reduce these risks.
- Kidney and Liver Function: Caution should be used if you have a history of kidney or liver problems, as Aceclofenac may affect their function.
- Pregnancy and Breastfeeding: Generally, Aceclofenac should be avoided during pregnancy, especially in the third trimester, as it may harm the fetus. It should be used with caution during breastfeeding and only if deemed absolutely necessary by a healthcare provider.
- Allergic Reactions: If you have a known allergy to other NSAIDs (such as aspirin), you should not take Aceclofenac.
Storage:
- Store Aceclo in a cool, dry place, away from moisture and direct light.
- Keep it out of the reach of children.
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