Description

CTD-T 12.5/40 Strip of 15 Tablets

Overview

CTD-T 12.5/40 is a combination antihypertensive medication containing Chlorthalidone 12.5 mg and Telmisartan 40 mg. It is prescribed for the effective management of high blood pressure (hypertension), especially in patients who are not adequately controlled with a single medicine. This fixed-dose combination provides long-lasting, steady, and superior blood pressure reduction by targeting multiple pathways responsible for hypertension.

Composition

Each film-coated tablet contains:

• Chlorthalidone IP – 12.5 mg

• Telmisartan IP – 40 mg

Description

CTD-T 12.5/40 combines a diuretic (water pill) with an angiotensin receptor blocker (ARB), offering enhanced antihypertensive action:

1. Chlorthalidone (12.5 mg)

A thiazide-like diuretic that:

• Increases the excretion of sodium and water

• Reduces blood volume

• Lowers pressure in the blood vessels

• Provides prolonged BP control (up to 48–72 hours)

The 12.5 mg dose is highly effective for sustained hypertension treatment.

2. Telmisartan (40 mg)

An angiotensin II receptor blocker (ARB) that:

• Relaxes and widens the blood vessels

• Blocks hormones that tighten arteries

• Reduces strain on the heart

• Offers 24-hour blood pressure control

Together, these medicines work synergistically to ensure stronger and more consistent BP reduction than either agent alone.

Uses

CTD-T 12.5/40 is prescribed for:

• Primary hypertension (essential hypertension)

• Patients not responding to monotherapy

• Reducing the risk of stroke and heart attack

• Protecting kidneys in hypertension or diabetes

• Long-term BP management in moderate to severe hypertension

This combination is especially beneficial for:

• Patients with high cardiovascular risk

• Those experiencing fluid retention

• Elderly patients with persistent hypertension

How CTD-T 12.5/40 Works

Chlorthalidone:

• Inhibits sodium-chloride reabsorption in the kidneys

• Removes excess fluid through increased urination

• Reduces total blood volume

• Lowers peripheral vascular resistance

Telmisartan:

• Blocks angiotensin II receptors

• Prevents blood vessel narrowing

• Decreases aldosterone levels

• Helps maintain smoother blood flow

These actions combine to deliver effective 24-hour blood pressure control, improved heart function, and reduced cardiovascular strain.

Benefits

• Stronger hypertension control due to dual therapy

• Long-acting effect allows once-daily dosing

• Reduces risk of heart attack, stroke, and kidney damage

• Suitable for long-term hypertension management

• Effective in salt-sensitive patients and the elderly

Side Effects

Most side effects are mild and temporary.

Common Side Effects:

• Frequent urination

• Dizziness or lightheadedness

• Fatigue

• Headache

• Dry mouth

Less Common Side Effects:

• Low potassium levels

• Low sodium

• Increased uric acid (possible gout flare)

• Muscle cramps

• Increased blood sugar

• Slight increase in creatinine

Precautions

• Regular BP monitoring is recommended

• Check electrolytes periodically

• Use with caution in kidney, liver, or heart disease

• Avoid potassium supplements unless prescribed

• Limit alcohol intake

• Not recommended during pregnancy

• Avoid excessive dehydration

Drug Interactions

CTD-T 12.5/40 may interact with:

• NSAIDs (may reduce effect)

• Lithium (risk of toxicity)

• ACE inhibitors or other ARBs

• Other diuretics

• Antidiabetic drugs

• Potassium supplements or salt substitutes

Storage

• Store below 25°C

• Protect from moisture and direct sunlight

• Keep in the original blister pack

• Keep out of reach of children