Endogest 400 Capsules 10′

Description

Endogest 400 is a medication containing Progesterone as its active ingredient. Progesterone is a hormone that plays a key role in the female reproductive system, particularly in regulating the menstrual cycle, supporting pregnancy, and promoting the development of the uterus lining. Endogest 400 contains 400 mg of Progesterone per capsule and is typically used in certain medical conditions related to hormone deficiency, pregnancy support, or menstrual disorders.

Active Ingredient:

• Progesterone (400 mg per capsule)

Uses of Endogest 400:

Endogest 400 (Progesterone) is commonly used for various medical indications, primarily related to female reproductive health. Some of the key uses include:

1. Hormonal Support during Pregnancy:
   • Progesterone supplementation is often prescribed in cases where low progesterone levels might affect the ability to sustain a pregnancy. It is commonly used in the early stages of pregnancy to prevent miscarriage or preterm labor.
   • It is especially used in cases of recurrent miscarriage or luteal phase defect (a condition in which the body does not produce enough progesterone to support the pregnancy).
2. Menstrual Disorders:
   • Progesterone can help regulate abnormal uterine bleeding and is used to treat conditions like irregular periods or heavy menstrual bleeding.
   • It is sometimes used to treat endometriosis, a condition where tissue similar to the uterine lining grows outside the uterus, causing pain and irregular bleeding.
3. Assisted Reproductive Technology (ART):
   • Progesterone is a key hormone used in in vitro fertilization (IVF) and other assisted reproductive procedures. It helps prepare the uterus lining (endometrium) for implantation of an embryo, enhancing the chances of pregnancy following IVF.
4. Hormone Replacement Therapy (HRT):
   • In combination with estrogen, progesterone is used in hormone replacement therapy (HRT) for postmenopausal women to relieve symptoms like hot flashes, night sweats, and vaginal dryness, while also protecting the uterus from the effects of estrogen-only therapy.
5. Treatment of Threatened Miscarriage:
   • Progesterone is often used in cases of threatened miscarriage to help support the pregnancy and prevent early labor in women who are experiencing complications like spotting or cramping.

How Endogest 400 (Progesterone) Works:

• Progesterone is a natural hormone produced by the ovaries (especially during the second half of the menstrual cycle) and the placenta during pregnancy.
• Progesterone prepares the uterus lining (endometrium) for pregnancy by helping it become thick and supportive for a fertilized egg to implant. If pregnancy does not occur, progesterone levels drop, leading to menstruation.
• When taken as a supplement, Endogest 400 provides additional progesterone, helping to correct any hormone deficiencies and support pregnancy, regulate menstruation, or prevent miscarriage.

Dosage and Administration:

• Typical Dosage: The dosage of Endogest 400 will depend on the medical condition being treated, the stage of pregnancy (if applicable), and the doctor’s recommendation.
  • For luteal phase support or early pregnancy: A common dose is 200–400 mg daily, which may be administered either as a single dose or divided into two doses.
  • For menstrual irregularities: The usual dose can range from 200 mg to 400 mg daily.
  • For Assisted Reproductive Technology (ART): The dose may be adjusted based on the specific ART protocol.
• Administration: Endogest 400 comes in capsule form and is typically taken by mouth. It is best taken with a full glass of water.
  • With or without food: Endogest capsules can be taken with or without food, but they should be swallowed whole (do not chew or break the capsule).
  • Time of day: It’s usually taken once daily or divided into two doses as prescribed.
• Missed Dose: If you miss a dose of Endogest 400, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose. Do not double up on doses to make up for a missed dose.

Side Effects of Endogest 400 (Progesterone):

Progesterone is generally well tolerated, but it can cause some side effects, particularly when used in higher doses or for prolonged periods. These include:

1. Common Side Effects:
   • Fatigue or tiredness
   • Dizziness
   • Headache
   • Nausea or vomiting
   • Breast tenderness or swelling
   • Bloating or stomach cramps
   • Mood changes, such as irritability or depression
   • Spotting or breakthrough bleeding (especially when starting treatment)
2. Serious Side Effects (Rare):
   • Severe allergic reactions (rash, itching, swelling of the face or throat, difficulty breathing)
   • Chest pain, shortness of breath, or swelling of the legs (which could indicate a blood clot)
   • Signs of liver problems: such as yellowing of the skin or eyes, dark urine, or persistent abdominal pain
   • Vision changes or blurry vision
   • Severe mood swings, depression, or thoughts of self-harm (especially if a history of depression exists)
3. Overdose: If you take more than the prescribed dose, seek immediate medical attention. Overdose symptoms can include drowsiness, nausea, and dizziness.

Precautions and Warnings:

• Pregnancy: Endogest 400 is used to support pregnancy in certain situations, but you should only use this medication under the supervision of your doctor, especially if you are pregnant or trying to conceive.
• Breastfeeding: Progesterone is generally considered safe during breastfeeding, but always consult your healthcare provider before starting any medication while breastfeeding.
• Allergic Reactions: If you experience hives, difficulty breathing, or swelling of your face or throat, seek immediate medical help as these may be signs of a severe allergic reaction.
• History of Blood Clots: If you have a history of deep vein thrombosis (DVT), pulmonary embolism, or stroke, inform your doctor before using Endogest 400, as progesterone can increase the risk of blood clots.
• Liver Function: If you have a history of liver disease, your doctor may monitor liver function during treatment with Endogest 400.
• Endometrial Cancer: Progesterone is sometimes used in hormone replacement therapy, but it should be used cautiously in individuals with a history of endometrial cancer (or any hormone-sensitive cancer).

Drug Interactions:

• Anticonvulsants: Certain anticonvulsants (such as phenytoin, carbamazepine) may reduce the effectiveness of progesterone.
• Antibiotics: Some antibiotics (like rifampin) may also decrease the effectiveness of Endogest 400.
• Other Hormonal Medications: Caution is required when combining Endogest with other hormonal medications, such as oral contraceptives, hormone replacement therapy, or fertility treatments.

Storage:

• Endogest 400 capsules should be stored at room temperature (15°C to 30°C), away from moisture and heat. Keep them in their original packaging to protect from light.
• Keep out of reach of children and do not use the medication after its expiration date.